红-白-蓝发射切换分子信标：比率型多色 DNA 杂交探针。
Red-white-blue emission switching molecular beacons: ratiometric multicolour DNA hybridization probes.
机构信息
Univeristy of Regensburg, Institute for Organic Chemistry, Universitätsstr. 31, D-93053 Regensburg, Germany.
出版信息
Org Biomol Chem. 2010 Feb 7;8(3):526-8. doi: 10.1039/b918381g. Epub 2009 Nov 25.
DOI:10.1039/b918381g
PMID:20090965
Abstract
Molecular beacons with two fluorophores derived from ethynyl pyrene and ethynyl nile red exhibit red emission in the hairpin that changes to blue through white upon binding to the target sequence with a dramatic shift of approximately 225 nm.
摘要
发夹构象中含有两个荧光团（来源于乙炔基芘和乙炔基尼罗红）的分子信标与目标序列结合后，发夹结构发生构象变化，从红色变为蓝色，荧光发射峰发生大约 225nm 的显著蓝移。
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