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[心脏性猝死无创风险分层的局限性与可能性]

[Limitations and possibilities of noninvasive risk stratification for sudden cardiac death].

作者信息

Tönnis Tobias, Kuck Karl-Heinz

机构信息

II. Medizinische Abteilung/Kardiologie, Asklepios Klinik St. Georg, Hamburg, Germany.

出版信息

Herz. 2009 Nov;34(7):506-16. doi: 10.1007/s00059-009-3290-x.

Abstract

Therapy of sudden cardiac death is dominated by the implantable cardioverter defibrillator (ICD), which is highly efficient, but also has side effects. Therefore, the adequate selection of patients who could benefit from this therapy is crucial. For risk stratification, left ventricular ejection fraction is basically used. It has, however, neither a high sensitivity nor a high specificity. Yet, its benefit has been proven in large randomized trials. Numerous noninvasive risk stratification parameters are available and still object of research to achieve a better prediction of sudden cardiac death than actually possible. This article gives an overview of the possibilities of noninvasive risk stratification and shows the concepts and the potential benefit.

摘要

心脏性猝死的治疗主要依靠植入式心脏复律除颤器(ICD),它效率很高,但也有副作用。因此,恰当选择能从该治疗中获益的患者至关重要。对于风险分层,基本采用左心室射血分数。然而,它既没有高敏感性也没有高特异性。不过,其益处已在大型随机试验中得到证实。有许多非侵入性风险分层参数可供使用,并且仍是研究对象,目的是实现比目前实际可能情况更好的心脏性猝死预测。本文概述了非侵入性风险分层的可能性,并展示了相关概念及潜在益处。

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