Cameron Ian D, Murray Geoff R, Gillespie Lesley D, Robertson M Clare, Hill Keith D, Cumming Robert G, Kerse Ngaire
Rehabilitation Studies Unit, Northern Clinical School, Sydney Medical School, The University of Sydney, PO Box 6, Ryde, NSW, Australia, 1680.
Cochrane Database Syst Rev. 2010 Jan 20(1):CD005465. doi: 10.1002/14651858.CD005465.pub2.
Falls in nursing care facilities and hospitals are common events that cause considerable morbidity and mortality for older people.
To assess the effectiveness of interventions designed to reduce falls by older people in nursing care facilities and hospitals.
We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (January 2009); the Cochrane Central Register of Controlled Trials (The Cochrane Library 2008, Issue 2); MEDLINE, EMBASE, and CINAHL (all to November 2008); trial registers and reference lists of articles.
Randomised controlled trials of interventions to reduce falls in older people in nursing care facilities or hospitals. Primary outcomes were rate of falls and risk of falling.
Two review authors independently assessed trial quality and extracted data. Data were pooled where appropriate.
We included 41 trials (25,422 participants).In nursing care facilities, the results from seven trials testing supervised exercise interventions were inconsistent. This was the case too for multifactorial interventions, which overall did not significantly reduce the rate of falls (rate ratio (RaR) 0.82, 95% CI 0.62 to 1.08; 7 trials, 2997 participants) or risk of falling (risk ratio (RR) 0.93, 95% CI 0.86 to 1.01; 8 trials, 3271 participants). A post hoc subgroup analysis, however, indicated that where provided by a multidisciplinary team, multifactorial interventions reduced the rate of falls (RaR 0.60, 95% CI 0.51 to 0.72; 4 trials, 1651 participants) and risk of falling (RR 0.85, 95% CI 0.77 to 0.95; 5 trials, 1925 participants). Vitamin D supplementation reduced the rate of falls (RaR 0.72, 95% CI 0.55 to 0.95; 4 trials, 4512 participants), but not risk of falling (RR 0.98, 95% CI 0.89 to 1.09; 5 trials, 5095 participants).In hospitals, multifactorial interventions reduced the rate of falls (RaR 0.69, 95% CI 0.49 to 0.96; 4 trials, 6478 participants) and risk of falling (RR 0.73, 95% CI 0.56 to 0.96; 3 trials, 4824 participants). Supervised exercise interventions showed a significant reduction in risk of falling (RR 0.44, 95% CI 0.20 to 0.97; 3 trials, 131 participants).
AUTHORS' CONCLUSIONS: There is evidence that multifactorial interventions reduce falls and risk of falling in hospitals and may do so in nursing care facilities. Vitamin D supplementation is effective in reducing the rate of falls in nursing care facilities. Exercise in subacute hospital settings appears effective but its effectiveness in nursing care facilities remains uncertain.
在护理机构和医院中,跌倒对于老年人来说是常见事件,会导致相当高的发病率和死亡率。
评估旨在减少护理机构和医院中老年人跌倒的干预措施的有效性。
我们检索了Cochrane骨、关节与肌肉创伤组专业注册库(2009年1月);Cochrane对照试验中心注册库(《Cochrane图书馆》2008年第2期);MEDLINE、EMBASE和CINAHL(均截至2008年11月);试验注册库以及文章的参考文献列表。
针对减少护理机构或医院中老年人跌倒的干预措施的随机对照试验。主要结局为跌倒发生率和跌倒风险。
两位综述作者独立评估试验质量并提取数据。在适当情况下对数据进行合并。
我们纳入了41项试验(25422名参与者)。在护理机构中,7项测试有监督的运动干预措施的试验结果不一致。多因素干预措施也是如此,总体上并未显著降低跌倒发生率(发生率比(RaR)0.82,95%置信区间0.62至1.08;7项试验,2997名参与者)或跌倒风险(风险比(RR)0.93,95%置信区间0.86至1.01;8项试验,3271名参与者)。然而,一项事后亚组分析表明,由多学科团队提供的多因素干预措施可降低跌倒发生率(RaR 0.60,95%置信区间0.51至0.72;4项试验,1651名参与者)和跌倒风险(RR 0.85,95%置信区间0.77至0.95;5项试验,1925名参与者)。补充维生素D可降低跌倒发生率(RaR 0.72,95%置信区间0.55至0.95;4项试验,4512名参与者),但不能降低跌倒风险(RR 0.98,95%置信区间0.89至1.09;5项试验,5095名参与者)。在医院中,多因素干预措施可降低跌倒发生率(RaR 0.69,95%置信区间0.49至0.96;4项试验,6478名参与者)和跌倒风险(RR 0.73,95%置信区间0.56至0.96;3项试验,4824名参与者)。有监督的运动干预措施显示跌倒风险显著降低(RR 0.44,95%置信区间0.20至0.97;3项试验,131名参与者)。
有证据表明多因素干预措施可降低医院中的跌倒发生率和跌倒风险,在护理机构中可能也有此效果。补充维生素D可有效降低护理机构中的跌倒发生率。亚急性医院环境中的运动似乎有效,但其在护理机构中的有效性仍不确定。