Meader Nicholas, Li Ryan, Des Jarlais Don C, Pilling Stephen
National Collaborating Centre for Mental Health, Royal College of Psychiatrists Research and Training Unit, University College, London, Standon House, 4th Floor, 21 Mansell Street, London, UK, E1 8AA.
Cochrane Database Syst Rev. 2010 Jan 20;2010(1):CD007192. doi: 10.1002/14651858.CD007192.pub2.
Drug users (including both injection drug users and crack cocaine users), are at high levels of risk for contracting HIV. Therefore it is important to reduce the injection and/or sexual risk behaviours of these groups both for the benefit of themselves and for society as a whole.
To assess the efficacy of multi-session psychosocial interventions in comparison with standard education and minimal intervention controls for the reduction of injection and sexual risk behaviour.
Electronic searches were conducted of a number of bibliographic databases (including Cochrane Library, CINAHL, MEDLINE, PsycINFO). In addition, other methods of locating papers were employed including contacting various authors working in the field of HIV risk reduction and examining reference lists of applicable papers identified in the electronic search.
The inclusion criteria consisted of randomised and quazi-randomised trials assessing the efficacy of psychosocial interventions in the reduction of injection and sexual risk behaviour for people who misused opiates, cocaine, or a combination of these drugs.
Two authors independently assessed the eligibility of studies identified by the search strategy, quality assessed these studies and extracted the data. A total of 35 trials met the eligibility criteria of the review providing data on 11,867 participants.
There were minimal differences identified between multi-session psychosocial interventions and standard educational interventions for both injection and sexual risk behaviour. Although it should be noted there were large pre-post changes for both groups suggesting both were effective in reducing risk behaviours. In addition, there was some evidence of benefit for multi-session psychosocial interventions when compared with minimal controls. Subgroup analyses suggest that people in formal treatment are likely to respond to multi-session psychosocial interventions. It also appears single-gender groups may be associated with greater benefit.
AUTHORS' CONCLUSIONS: There is limited support for the widespread use of formal multi-session psychosocial interventions for reducing injection and sexual risk behaviour. Brief standard education interventions appear to be a more cost-effective option. Further research is required to assess if there are particular groups of drug users more likely to respond to such interventions.
吸毒者(包括注射吸毒者和快克可卡因使用者)感染艾滋病毒的风险很高。因此,减少这些群体的注射和/或性风险行为,对他们自身以及整个社会都有益处,这一点很重要。
评估多阶段社会心理干预措施相较于标准教育和最小干预对照组,在减少注射和性风险行为方面的效果。
对多个文献数据库(包括考克兰图书馆、护理学与健康领域数据库、医学索引数据库、心理学文摘数据库)进行了电子检索。此外,还采用了其他查找论文的方法,包括联系从事艾滋病毒风险降低领域工作的各位作者,并查阅在电子检索中找到的相关论文的参考文献列表。
入选标准包括随机和半随机试验,这些试验评估社会心理干预措施在减少滥用鸦片类药物、可卡因或这两种药物组合的人群的注射和性风险行为方面的效果。
两位作者独立评估检索策略所识别研究的合格性,对这些研究进行质量评估并提取数据。共有35项试验符合该综述的入选标准,提供了11867名参与者的数据。
在减少注射和性风险行为方面,多阶段社会心理干预措施与标准教育干预措施之间的差异极小。不过应当指出的是,两组干预前后都有很大变化,表明两者在减少风险行为方面均有效。此外,与最小干预对照组相比,有一些证据表明多阶段社会心理干预措施有益。亚组分析表明,接受正规治疗的人可能对多阶段社会心理干预措施有反应。似乎单性别群体可能获益更大。
广泛使用正规的多阶段社会心理干预措施来减少注射和性风险行为,得到的支持有限。简短的标准教育干预措施似乎是更具成本效益的选择。需要进一步研究,以评估是否有特定的吸毒者群体更可能对这类干预措施有反应。