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一项针对减少注射吸毒者丙型肝炎病毒风险行为的简短行为干预措施的随机对照试验。

Randomized controlled trial of a brief behavioural intervention for reducing hepatitis C virus risk practices among injecting drug users.

作者信息

Tucker Thamizan, Fry Craig L, Lintzeris Nick, Baldwin Simon, Ritter Alison, Donath Susan, Whelan Greg

机构信息

Turning Point Alcohol and Drug Centre, Melbourne, Victoria, Australia.

出版信息

Addiction. 2004 Sep;99(9):1157-66. doi: 10.1111/j.1360-0443.2004.00809.x.

DOI:10.1111/j.1360-0443.2004.00809.x
PMID:15317636
Abstract

AIM

To develop and evaluate a brief intervention for reducing risk behaviours associated with HCV transmission in injecting drug users (IDU).

DESIGN

Randomized controlled trial of an individually tailored brief behavioural intervention (BBI) (experimental) versus a standardized educational intervention (control).

SETTING

Specialist drug treatment facility in Melbourne, Australia.

PARTICIPANTS

One hundred and forty-five IDU (aged 18 or over, injecting at least weekly in the preceding 6 months) recruited and randomized to the experimental condition (n = 73) or the control condition (n = 72).

INTERVENTIONS

The BBI was based on the Blood-Borne Virus Transmission Risk Assessment Questionnaire (BBV-TRAQ)-a standardized blood-borne virus risk assessment instrument comprising injecting risk, sexual risk and other skin penetration risk subscales. The BBV-TRAQ was used to identify individual HCV risk practices and to tailor the 30-minute experimental BBI. Control participants received a standardized HCV educational session, using current educational materials.

MAIN OUTCOME MEASURES

BBV-TRAQ subscale and total scores and measures of participant satisfaction.

RESULTS

One hundred and twenty-four participants (86%) were followed-up at 4 weeks (+/-7 days). Analyses revealed a significant reduction in HCV risk behaviours for both groups at 1-month follow-up, with participants in the experimental BBI condition reporting higher overall satisfaction with the intervention compared to the control group.

CONCLUSIONS

Both groups reported significant reductions in risk behaviour, indicating that while BBI methods hold promise for HCV education and prevention, they were not demonstrated to be more effective than the provision of standard educational materials. Future research could evaluate the efficacy of the BBV-TRAQ as a risk behaviour intervention and counselling tool in clinical, NSP and peer education settings.

摘要

目的

开发并评估一种简短干预措施,以减少注射吸毒者(IDU)中与丙型肝炎病毒(HCV)传播相关的风险行为。

设计

一项针对个体定制的简短行为干预(BBI)(实验组)与标准化教育干预(对照组)的随机对照试验。

地点

澳大利亚墨尔本的专业戒毒治疗机构。

参与者

招募了145名注射吸毒者(年龄在18岁及以上,在过去6个月中至少每周注射一次),并随机分为实验组(n = 73)或对照组(n = 72)。

干预措施

BBI基于血源性病毒传播风险评估问卷(BBV-TRAQ)——一种标准化的血源性病毒风险评估工具,包括注射风险、性风险和其他皮肤穿刺风险子量表。BBV-TRAQ用于识别个体HCV风险行为,并定制30分钟的实验性BBI。对照组参与者使用当前的教育材料接受标准化的HCV教育课程。

主要观察指标

BBV-TRAQ子量表和总分以及参与者满意度测量。

结果

124名参与者(86%)在4周(±7天)时接受了随访。分析显示,在1个月随访时,两组的HCV风险行为均显著减少,与对照组相比,接受实验性BBI的参与者对干预的总体满意度更高。

结论

两组均报告风险行为显著减少,这表明虽然BBI方法在HCV教育和预防方面有前景,但未证明其比提供标准教育材料更有效。未来的研究可以评估BBV-TRAQ作为临床、针具交换计划(NSP)和同伴教育环境中风险行为干预和咨询工具的效果。

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