Baka-Ostrowska Małgorzata
Pediatric Urology Department Children's Memorial Health Institute, Warsaw, Poland.
Cent European J Urol. 2011;64(4):237-9. doi: 10.5173/ceju.2011.04.art11. Epub 2011 Dec 9.
Posterior urethral valve (PUV) is a condition that leads to characteristic changes in the bladder and upper urinary tract. Dysfunction of the bladder such as a hyperreflective, hypertonic, and small capacity bladder as well as sphincter incompetence and/or myogenic failure should be adequately treated. Poor compliance/small bladder could be treated with anticholinergics, but bladder augmentation will probably be indicated. Although bladder reconstruction with gastrointestinal segments can be associated with multiple complications, including metabolic disorders, calculus formation, mucus production, enteric fistulas, and malignancy formation, enterocystoplasty is still the gold standard. In contrast to a neuropathic or exstrophic bladder, augmentation of the valve bladder allows spontaneous voiding without significant residual urine in the majority of cases, but some require CIC (clean intermittent cathterization). Augmentation cystoplasty is also an efficient approach in those children who will require kidney transplantation in the future.
后尿道瓣膜症(PUV)是一种导致膀胱和上尿路出现特征性变化的病症。膀胱功能障碍,如膀胱反射亢进、高张性、小容量膀胱以及括约肌功能不全和/或肌源性衰竭,都应得到充分治疗。顺应性差/小膀胱可用抗胆碱能药物治疗,但可能需要进行膀胱扩大术。尽管使用胃肠道段进行膀胱重建可能会伴有多种并发症,包括代谢紊乱、结石形成、黏液分泌、肠瘘和恶性肿瘤形成,但肠膀胱扩大术仍是金标准。与神经性或膀胱外翻不同,瓣膜性膀胱扩大术在大多数情况下可使患者自主排尿且残余尿量不多,但有些患者需要进行清洁间歇性导尿(CIC)。对于未来需要进行肾移植的儿童,膀胱扩大成形术也是一种有效的治疗方法。