Pediatric Urology Research Center, Department of Urology, Tehran University of Medical Sciences, Tehran, Iran.
J Urol. 2010 Mar;183(3):1168-74. doi: 10.1016/j.juro.2009.11.052. Epub 2010 Jan 22.
We present the long-term results of simultaneous "teapot" ureterocystoplasty and ureteral Mitrofanoff in patients with bilateral megaureters due to neurogenic bladder, and compare urodynamic results before and after the procedure.
We treated 13 children (mean age 7.3 years) with end stage neurogenic bladder and refluxing megaureters (mean diameter 5.5 cm) with simultaneous teapot ureterocystoplasty and Mitrofanoff appendicovesicostomy between April 1995 and May 2001. The larger ureter was used for teapot bladder augmentation while keeping its distal 2 cm tubularized. The Mitrofanoff channel was then created using the opposite ureter.
Followup ranged from 109 to 169 months (median 121). At the end of the followup period all patients were dry with clean intermittent catheterization and/or voiding. No repeat augmentation was needed and there were no bladder calculi during followup. Median postoperative bladder capacity was 430 ml (IQR 380 to 477), which was increased significantly compared to preoperative evaluations (210 ml, IQR 181 to 230, p = 0.001). During followup bladder compliance also improved significantly (p = 0.001) and serum creatinine level decreased (p = 0.021).
Although neurogenic bladder and high grade reflux are poor prognostic factors for ureterocystoplasty, the present modification resulted in enduring bladder augmentation with no calculus formation. Bladders remained compliant with good capacity, presumably because sufficient tissue and blood supply were provided for the augmented flap.
我们介绍了双侧巨输尿管症神经源性膀胱患者同期“茶壶”输尿管膀胱成形术和输尿管米托法诺夫(Mitrofanoff)吻合术的长期结果,并比较了手术前后的尿动力学结果。
1995 年 4 月至 2001 年 5 月,我们治疗了 13 例终末期神经源性膀胱和反流性巨输尿管症(平均直径 5.5cm)患儿,同期行茶壶状输尿管膀胱成形术和米托法诺夫阑尾膀胱吻合术。较大的输尿管用于茶壶状膀胱扩大,同时保持其远端 2cm 管状化。然后使用对侧输尿管创建米托法诺夫通道。
随访时间为 109 至 169 个月(中位数 121 个月)。随访期末,所有患者均能通过间歇性清洁导尿或自主排尿实现完全控尿。无需再次行膀胱扩大术,随访期间无膀胱结石形成。术后膀胱容量中位数为 430ml(IQR 380 至 477),与术前评估相比显著增加(210ml,IQR 181 至 230,p=0.001)。随访期间,膀胱顺应性也显著改善(p=0.001),血清肌酐水平降低(p=0.021)。
尽管神经源性膀胱和高级别反流是输尿管膀胱成形术的不良预后因素,但本研究中的改良方法可实现持久的膀胱扩大,且无结石形成。膀胱仍保持顺应性和良好的容量,可能是因为扩大瓣得到了足够的组织和血液供应。