Johal Navroop S, Hamid Rizwan, Aslam Zeeshan, Carr Brig, Cuckow Peter M, Duffy Patrick G
Department of Pediatric Urology, Great Ormond Street Hospital for Children, London, United Kingdom.
J Urol. 2008 Jun;179(6):2373-5; discussion 2376. doi: 10.1016/j.juro.2008.01.170. Epub 2008 Apr 23.
Many institutions have reported varied levels of success with ureterocystoplasty. Recently, there have been concerns regarding the efficacy of ureterocystoplasty as a form of bladder augmentation. We report our long-term functional outcomes with the procedure based on the experience of a single surgeon.
A total of 17 procedures were performed during a 12-year period. Of the patients 10 had posterior urethral valves, 3 had bladder exstrophy, 2 had a neuropathic bladder, 1 had a cloacal anomaly and 1 had a left ectopic ureter. Mean patient age at operation was 5.9 years (range 0.3 to 14.2). All patients underwent preoperative ultrasound, urodynamic studies and radionuclide scanning. Postoperative urodynamics were performed at 6 months.
Followup ranged from 0.5 to 11.5 years (mean 4.5). Nine patients underwent ureterocystoplasty with preservation of the ipsilateral kidney, and 1 underwent ureterocystoplasty alone and had a solitary right kidney. The remaining 7 patients underwent ureterocystoplasty with ipsilateral nephrectomy. Postoperatively, the mean bladder capacity improved from 125 to 292 ml, while the mean end filling pressure decreased from 72 to 22 cm H(2)O. Mean preoperative system compliance was 2.1 ml/cm H(2)O, which increased to 16.2 ml/cm H(2)O postoperatively. A total of 13 patients did not require further augmentation surgery. The remaining 4 patients had high pressure and poorly compliant bladders, and underwent ileocystoplasty. Subsequent postoperative nucleotide scans in these 4 patients demonstrated stable upper tracts with good drainage.
Based on our results, ureterocystoplasty provides durable functional urodynamic improvement in patients with a megaureter.
许多机构报道了输尿管膀胱成形术的不同成功率。最近,人们对输尿管膀胱成形术作为膀胱扩大术的疗效存在担忧。我们根据一位外科医生的经验报告该手术的长期功能结果。
在12年期间共进行了17例手术。患者中,10例患有后尿道瓣膜,3例患有膀胱外翻,2例患有神经源性膀胱,1例患有泄殖腔畸形,1例患有左侧异位输尿管。手术时患者的平均年龄为5.9岁(范围0.3至14.2岁)。所有患者均接受了术前超声、尿动力学研究和放射性核素扫描。术后6个月进行尿动力学检查。
随访时间为0.5至11.5年(平均4.5年)。9例患者在保留同侧肾脏的情况下进行了输尿管膀胱成形术,1例仅进行了输尿管膀胱成形术且为孤立右肾。其余7例患者在进行输尿管膀胱成形术的同时进行了同侧肾切除术。术后,膀胱平均容量从125毫升增加到292毫升,而平均充盈末压力从72厘米水柱降至22厘米水柱。术前平均系统顺应性为2.1毫升/厘米水柱,术后增加到16.2毫升/厘米水柱。共有13例患者无需进一步的扩大手术。其余4例患者膀胱压力高且顺应性差,接受了回肠膀胱成形术。这4例患者术后随后的核苷酸扫描显示上尿路稳定且引流良好。
根据我们的结果,输尿管膀胱成形术可使巨输尿管患者的尿动力学功能得到持久改善。