CONRAD, Atlanta, Georgia, USA.
J Womens Health (Larchmt). 2010 Feb;19(2):329-34. doi: 10.1089/jwh.2009.1387.
To compare maternal and fetal outcomes among women with and without diagnosed depression at the time of delivery.
Hospital discharge data from the 1998-2005 Nationwide Inpatient Sample (NIS) were used to examine delivery-related hospitalizations for select maternal and fetal outcomes by depression diagnosis.
The rate of depression per 1000 deliveries increased significantly from 2.73 in 1998 to 14.1 in 2005 (p < 0.001). Women diagnosed with depression were significantly more likely to have cesarean delivery, preterm labor, anemia, diabetes, and preeclampsia or hypertension compared with women without depression. Fetal outcomes significantly associated with maternal depression were fetal growth restriction, fetal abnormalities, fetal distress, and fetal death.
These findings suggest that depression is associated with adverse maternal and fetal outcomes. Our results provide additional impetus to screen for depression among women of reproductive age, especially those who plan to become pregnant.
比较分娩时患有和未患有抑郁症的女性的母婴结局。
使用 1998 年至 2005 年全国住院患者样本（NIS）的住院数据，根据抑郁诊断，检查与分娩相关的特定母婴结局的住院情况。
每 1000 例分娩中抑郁症的发生率从 1998 年的 2.73 显著增加到 2005 年的 14.1（p < 0.001）。与没有抑郁症的女性相比，诊断为抑郁症的女性更有可能进行剖宫产、早产、贫血、糖尿病、子痫前期或高血压。与产妇抑郁显著相关的胎儿结局包括胎儿生长受限、胎儿畸形、胎儿窘迫和胎儿死亡。
这些发现表明，抑郁症与母婴不良结局有关。我们的研究结果为在育龄妇女中，特别是那些计划怀孕的妇女中筛查抑郁症提供了更多的动力。
