Radboud University Nijmegen Medical Centre, Scientific Institute for Quality of Health Care, 6500 HB Nijmegen, The Netherlands.
BMC Musculoskelet Disord. 2010 Jan 24;11:14. doi: 10.1186/1471-2474-11-14.
Manual Therapy applied to patients with non specific neck pain has been investigated several times. In the Netherlands, manual therapy as applied according to the Utrecht School of Manual Therapy (MTU) has not been the subject of a randomized controlled trial. MTU differs in diagnoses and treatment from other forms of manual therapy.
METHODS/DESIGN: This is a single blind randomized controlled trial in patients with sub-acute and chronic non specific neck pain. Patients with neck complaints existing for two weeks (minimum) till one year (maximum) will participate in the trial. 180 participants will be recruited in thirteen primary health care centres in the Netherlands.The experimental group will be treated with MTU during a six week period. The control group will be treated with physical therapy (standard care, mainly active exercise therapy), also for a period of six weeks.Primary outcomes are Global Perceived Effect (GPE) and functional status (Neck Disability Index (NDI-DV)). Secondary outcomes are neck pain (Numeric Rating Scale (NRS)), Eurocol, costs and quality of life (SF36).
This paper presents details on the rationale of MTU, design, methods and operational aspects of the trial.
ClinicalTrials.gov Identifier: NCT00713843.
针对非特异性颈部疼痛患者的手法治疗已被多次研究。在荷兰，根据乌得勒支手法治疗学派（MTU）实施的手法治疗尚未进行随机对照试验。MTU 在诊断和治疗方面与其他形式的手法治疗不同。
方法/设计：这是一项针对亚急性和慢性非特异性颈部疼痛患者的单盲随机对照试验。患有颈部疼痛的患者将参与试验，其症状持续时间为两周（最短）至一年（最长）。将在荷兰的 13 个初级保健中心招募 180 名参与者。实验组将在六周内接受 MTU 治疗。对照组将接受物理治疗（标准护理，主要是主动运动疗法），同样为期六周。主要结局指标是总体感知效果（GPE）和功能状态（颈部残疾指数（NDI-DV））。次要结局指标是颈部疼痛（数字评分量表（NRS））、Eurocol、成本和生活质量（SF36）。
本文介绍了 MTU 的基本原理、设计、方法和试验操作细节。
ClinicalTrials.gov 标识符：NCT00713843。
