影响多巴胺神经元和打哈欠行为的药物。
Drugs affecting dopamine neurons and yawning behavior.
作者信息
Mogilnicka E, Klimek V
出版信息
Pharmacol Biochem Behav. 1977 Oct;7(4):303-5. doi: 10.1016/0091-3057(77)90224-6.
PMID:200963
Abstract
Drugs stimulating the dopamine (DA) neurons in different ways (apomorphine, piribedil, amphetamine, nomifensine, L-DOPA) given in low doses (not producing behavioral excitation) induced yawning in rats. Blockade of DA receptors with neuroleptics counteracted DA-agonists induced yawning which may indicate a dopaminergic component of this behavior.
摘要
以不同方式刺激多巴胺（DA）神经元的药物（阿扑吗啡、吡贝地尔、苯丙胺、诺米芬辛、左旋多巴）低剂量给药（不产生行为兴奋）可诱导大鼠打哈欠。用抗精神病药物阻断DA受体会抵消DA激动剂诱导的打哈欠，这可能表明该行为存在多巴胺能成分。
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