Medical Toxicology Centre, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE3 2DX, UK.
Trans R Soc Trop Med Hyg. 2010 May;104(5):320-7. doi: 10.1016/j.trstmh.2009.12.006. Epub 2010 Jan 22.
The demographics, epidemiology, first aid, clinical management, treatment and outcome of snake bites causing no significant signs of systemic envenoming were documented in Chittagong Medical College Hospital, Bangladesh, between May 1999 and October 2002. Among 884 patients admitted, 350 were systemically envenomed and 534 were without signs of either systemic or significant local envenoming. The average age of patients with physical evidence of snake bite but no systemic envenoming was 26.4 years. Most had been bitten on their feet or hands. Ligatures had been applied proximal to the bite site in >95% of cases and the bite site had been incised in 13%. Patients were typically discharged at 24h. Those with clinical signs of systemic envenoming resembled the non-envenomed cases demographically and epidemiologically except that they arrived at hospital significantly later than non-envenomed patients, having spent longer with traditional healers. No non-envenomed patient was treated with antivenom and none went on to develop symptoms of systemic envenoming after discharge. The potential complications and confusing signs caused by ligatures and incision demand that all patients admitted with a history of snake bite be kept under observation for 24h after admission even if they have no signs of systemic envenoming.
1999 年 5 月至 2002 年 10 月期间,在孟加拉国吉大港医学院附属医院记录了导致无明显全身中毒迹象的蛇咬伤的人口统计学、流行病学、急救、临床管理、治疗和结果。在入院的 884 名患者中,有 350 名患者出现全身中毒,534 名患者既无全身中毒迹象也无明显局部中毒迹象。有蛇咬伤物理证据但无全身中毒迹象的患者的平均年龄为 26.4 岁。大多数人被咬伤在脚部或手部。在超过 95%的情况下,在咬伤部位近端应用了结扎,有 13%的病例对咬伤部位进行了切开。患者通常在 24 小时内出院。出现全身中毒临床症状的患者在人口统计学和流行病学方面与未中毒的患者相似,除了他们比未中毒的患者到达医院的时间明显晚,而且在传统治疗师那里停留的时间更长。没有未中毒的患者接受抗蛇毒血清治疗,也没有患者在出院后出现全身中毒症状。结扎和切开造成的潜在并发症和混淆迹象要求所有入院时有蛇咬伤史的患者在入院后 24 小时内接受观察,即使他们没有全身中毒迹象。