Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, PO Box 114-D, Santiago, Chile.
Plant Physiol Biochem. 2010 Feb-Mar;48(2-3):194-9. doi: 10.1016/j.plaphy.2009.12.009. Epub 2010 Jan 11.
Histone acetyltransferases (HATs) and deacetylases (HDACs) play critical roles in the regulation of chromatin structure and gene expression. In plants, these genes are emerging as crucial players in all aspects of development. As part of our study regarding the growth and development of grapevine (Vitis vinifera), we report the genome-wide analysis of HAT and HDAC genes. This analysis revealed the presence of 7 and 13 genes coding for putative HATs and HDACs, respectively. In this work, we present a complete analysis of these families with regards to their phylogenetic relationships with orthologous genes identified in other sequenced plant genomes, their genome location, gene structure and expression. The genes identified can be grouped into different families as has been previously described for other eukaryotic species. The organ-specific expression pattern of HAT and HDAC genes indicates that some genes have different expression profiles, and their potential involvement during grape development is discussed.
组蛋白乙酰转移酶（HATs）和去乙酰化酶（HDACs）在调节染色质结构和基因表达方面发挥着关键作用。在植物中，这些基因作为发育各个方面的关键参与者而崭露头角。作为我们关于葡萄（Vitis vinifera）生长和发育研究的一部分，我们报告了 HAT 和 HDAC 基因的全基因组分析。该分析显示，分别有 7 个和 13 个基因编码推测的 HAT 和 HDAC。在这项工作中，我们对这些家族进行了全面分析，包括与其他已测序植物基因组中鉴定的同源基因的系统发育关系、它们在基因组中的位置、基因结构和表达。鉴定出的基因可以分为不同的家族，如以前在其他真核生物中描述的那样。HAT 和 HDAC 基因的组织特异性表达模式表明，一些基因具有不同的表达谱，并讨论了它们在葡萄发育过程中的潜在参与。
