Dilsaver Steven C, Benazzi Franco, Oedegaard Ketil J, Fasmer Ole B, Akiskal Kareen K, Akiskal Hagop S
Comprehensive Doctors Medical Group, Inc, Arcadia, California and The Mental Health Mental Retardation Clinic, Rio Grande City, Texas, USA.
Prim Care Companion J Clin Psychiatry. 2009;11(6):302-6. doi: 10.4088/PCC.08m00728.
The objective of this cross-sectional study was to determine the prevalence of migraine headache among depressed Latino adults of Mexican American origin meeting the criteria for bipolar disorder (BPD) or major depressive disorder (MDD) relative to patients in a psychiatric comparison group.
In a mental health clinic for the indigent, consecutively and systematically evaluated acutely depressed Latino adults received structured diagnostic psychiatric interviews based on modules extracted from the Structured Clinical Interview for DSM-IV. All were asked as part of routine assessment whether they had headaches "in the last week." Patients with unilateral, pounding, pulsating headache were classified as having migraine headache. The prevalence of migraine headache among the patients with BPD and MDD was contrasted with that of patients in a psychiatric comparison group composed of patients with disorders other than schizophrenia or schizoaffective disorder. Logistic regression was used to test for associations and control for confounding effects. The data were collected between August 2001 and November 2004.
Eighty-seven patients had BPD and 123 had MDD. Bipolar patients were 2.9 times more likely to have migraine headaches than patients with MDD (P < .0001). There was a trend for patients with MDD to have a higher prevalence of migraine than patients in the psychiatric comparison group.
Bipolar patients had a high prevalence of migraine headache relative to patients with MDD. This study suggests that migraine is linked to bipolarity.
本横断面研究的目的是确定符合双相情感障碍（BPD）或重度抑郁症（MDD）标准的墨西哥裔美国抑郁症拉丁裔成年人中偏头痛的患病率，并与精神科对照组的患者进行比较。
在一家为贫困人口服务的心理健康诊所，对急性抑郁的拉丁裔成年人进行连续且系统的评估，他们接受了基于从《精神疾病诊断与统计手册》第四版（DSM-IV）结构化临床访谈中提取的模块进行的结构化诊断性精神科访谈。作为常规评估的一部分，所有患者都被问及“上周”是否有头痛。单侧、搏动性头痛的患者被归类为患有偏头痛。将双相情感障碍和重度抑郁症患者中偏头痛的患病率与由非精神分裂症或分裂情感性障碍患者组成的精神科对照组患者的患病率进行对比。使用逻辑回归来检验关联并控制混杂效应。数据收集于2001年8月至2004年11月之间。
87名患者患有双相情感障碍，123名患者患有重度抑郁症。双相情感障碍患者患偏头痛的可能性是重度抑郁症患者的2.9倍（P < .0001）。重度抑郁症患者的偏头痛患病率有高于精神科对照组患者的趋势。
相对于重度抑郁症患者，双相情感障碍患者偏头痛的患病率较高。这项研究表明偏头痛与双相情感障碍有关。
