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新生大鼠反常睡眠的药理学抑制(作者译)

[Pharmacological suppression of paradoxical sleep in the newborn rat (author's transl)].

作者信息

Valatx J L, Nowaczyck T

出版信息

Rev Electroencephalogr Neurophysiol Clin. 1977 Jul-Sep;7(3):269-72. doi: 10.1016/s0370-4475(77)80004-x.

Abstract

In an attempt to suppress paradoxical sleep (PS) an intracerebral injection of 6 0HDA was carried out on rat faetuses at a gestational age of 16-20 days. In these animals a delay in maturation occurred compared to controls, the only modification of sleep being observed however, related to the circadian rhythmn of PS. The possible reasons for this are discussed within the framework of a concept relating paradoxical sleep to cerebral maturation.

摘要

为了抑制异相睡眠(PS),在妊娠16 - 20天的大鼠胎儿脑内注射了6 - 羟基多巴胺(6 - OHDA)。与对照组相比,这些动物出现了成熟延迟的情况,不过观察到的唯一睡眠改变与异相睡眠的昼夜节律有关。本文在将异相睡眠与大脑成熟相关的概念框架内讨论了其可能原因。

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