Lozano A M Pascual, Lázaro R Chamarro, Andrés J M Laínez
Servicio de Neurologia, Hospital Clinico Universitario, Valencia, Spain.
Neurologia. 2009 Nov;24(9):797-803.
We analyze the immediate and long-term clinical and angiographic results of endovascular treatment of ruptured and unruptured aneurysms in our single-center experience.
Between January of 1996 and June of 2005, 145 aneurysms were treated endovascularly in 137 patients. The clinical follow-up was performed during hospitalization and then for at least one year (mean, 40 months) in the out-patient clinic. The results of the angiographic follow-up that was completed by 64.9% of the patients (mean: 33 months) were analyzed.
Initially, complete occlusion was obtained in 64.8% and partial (sac or neck remnant) in 22.1%. There were technique failures in 12 cases. Overall morbidity associated to the procedure was 8.1%. There was no case of direct mortality and only one case of post-embolization re-bleeding. Rate of complete final occlusion was 78.6 and recanalization 7.5%. Partial occlusion and recanalization rates correlated with aneurysm geometry (simple or complex), neck size and posterior localization. Age, clinical state at admission (Hunt-Hess grade III-V), time of treatment and the concomitant intraventricular hemorrhage correlated with worse clinical outcome (Rankin III-V) at day 90 (p<0.05).
In our experience, endovascular treatment is an effective and safe technique for cerebral aneurysms. Rate of morbidity and the only case of long recanalization demonstrate the procedure safety and stability of the middle-long term results. The large experience of our radiologists and the incorporation of new technical modalities have allowed us to improve the results, above all, in recent years.
我们根据单中心经验分析了破裂和未破裂动脉瘤血管内治疗的近期和长期临床及血管造影结果。
1996年1月至2005年6月期间,对137例患者的145个动脉瘤进行了血管血管内治疗。在住院期间进行临床随访,然后在门诊至少随访一年(平均40个月)。分析了64.9%的患者完成的血管造影随访结果(平均:33个月)。
最初,完全闭塞率为64.8%,部分(瘤囊或瘤颈残留)闭塞率为22.1%。有12例技术失败。与该手术相关的总体发病率为8.1%。无直接死亡病例,仅1例栓塞后再出血。最终完全闭塞率为78.6%,再通率为7.5%。部分闭塞和再通率与动脉瘤形态(简单或复杂)、瘤颈大小及后循环定位相关。年龄、入院时临床状态(Hunt-Hess分级III-V级)、治疗时间及合并的脑室内出血与90天时较差的临床结局(Rankin分级III-V级)相关(p<0.05)。
根据我们的经验,血管内治疗是一种治疗脑动脉瘤的有效且安全的技术。发病率及仅有的一例长期再通病例证明了该手术的安全性及中长期结果的稳定性。我们放射科医生丰富的经验及新技术的应用使我们得以改善治疗结果,尤其是近年来。