C.J.Gorter Center for High Field Magnetic Resonance Imaging, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Magn Reson Med. 2010 Feb;63(2):297-302. doi: 10.1002/mrm.22262.
Using a small resonant loop to produce a longitudinal traveling wave on a human 7-T system allows MR to be performed over the entire volume of the human leg. We have used this capability to perform localized proton MR spectroscopy of the lipid composition of muscle in volunteers with a coil placed approximately 30 cm away from the region of interest. Spectra with a reasonable signal-to-noise ratio can be acquired in a clinically relevant data acquisition time of less than 5 min using the loop in transmit/receive mode, maintaining the full flexibility to acquire spectra from any part of the calf and/or thigh. If a local receive coil is used in combination with the remote transmit coil, then the signal-to-noise improves significantly, as expected.
利用小的谐振环在人体 7-T 系统上产生纵向行波，可使磁共振能够在人体腿部的整个容积上进行。我们利用这一功能，在志愿者身上，通过将线圈放置在距离感兴趣区域约 30 厘米处，对肌肉的脂质组成进行局部质子磁共振波谱分析。使用环形收发模式，在不到 5 分钟的临床相关数据采集时间内，可以获得具有合理信噪比的光谱，保持从小腿和/或大腿的任何部位采集光谱的完全灵活性。如果将局部接收线圈与远程发射线圈结合使用，则信噪比会显著提高，这是预期的结果。
