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来自阿尔及利亚的胡萝卜中的生物活性苯丙素类化合物。

Bioactive phenylpropanoids from Daucus crinitus Desf. from Algeria.

机构信息

Université de Corse-CNRS, UMR 6134 SPE, Equipe Chimie et Biomasse, Route des Sanguinaires, 20000 Ajaccio, France.

出版信息

J Agric Food Chem. 2010 Feb 24;58(4):2174-9. doi: 10.1021/jf903760b.

DOI:10.1021/jf903760b
PMID:20099856
Abstract

The volatile constituents of Daucus crinitus Desf. from Algeria were analyzed by GC and GC-MS, The main constituent was isochavicol isobutyrate (39.0%), an uncommon phenylpropanoid. By synthesis of a series of homologous esters, it was also possible to determine the presence of small amounts of isochavicol propionate, which has never been described previously as a natural product. The antibacterial and antifungal activities of the whole essential oil, of these two esters, and of isochavicol itself were investigated against a wide range of bacteria and fungi. Additionally, their antimalarial and antiradical properties were also evaluated, showing an interesting antiplasmodial activity of isochavicol.

摘要

从阿尔及利亚的欧防风中分析出的挥发性成分,采用气相色谱法和气相色谱-质谱法进行分析。主要成分是异土木香酚异丁酸酯(39.0%),这是一种不常见的苯丙素。通过合成一系列同源酯,还可以确定以前从未被描述为天然产物的少量异土木香基丙酸酯的存在。对各种细菌和真菌进行了全精油、这两种酯以及异土木香酚本身的抗菌和抗真菌活性研究。此外,还评估了它们的抗疟疾和抗自由基特性,表明异土木香酚具有有趣的抗疟原虫活性。

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引用本文的文献

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