Bendiabdellah Amel, El Amine Dib Mohammed, Djabou Nassim, Allali Hocine, Tabti Boufeldja, Muselli Alain, Costa Jean
UMR CNRS 6134, Laboratoire Chimie des Produits Naturels, Campus Grimaldi, Université de Corse, BP 52, 20250, Corte, France.
Chem Cent J. 2012 May 30;6(1):48. doi: 10.1186/1752-153X-6-48.
In order to find new bioactive natural products, the antimicrobial and antioxidant activities of essential oil components extracted from the separated organs of the Algerian medicinal and aromatic plant Daucus muricatus L. were studied.
The chemical composition of essential oils obtained by hydrodistillation (HD) was investigated using Gas Chromatography-Retention Indices (GC-RI) and GC-Mass Spectrometry (GC-MS). Two types of essential oils were produced by D. muricatus: (i) The oil from roots is mainly composed by nonterpenic oxygenated compounds (59.8 g/100 g), and (ii) the aerial part oils (i.e., the leaves, stems, flowers, and umbels) was mainly composed by terpenic hydrocarbon compounds (62.3-72.2 g/100 g). The chemical composition of the volatile fraction isolated from different organs of Daucus muricatus were studied by HS-SPME/GC-RI and GC-MS after optimization of Solid Phase MicroExtraction parameters. For all organs studied, the main volatiles emitted by the plant were hydrocarbon compounds (60.7-82.2 g/100 g). Only quantitative differences between the volatiles of the separated organs studied were observed. In addition, the activity of the oil of D. muricatus against eight bacterial strains and one yeast was investigated. The oil from roots revealed active against S. aureus, while the essential oil obtained from the aerial parts was active against the yeast C. albicans.
Daucus muricatus essential oil seems be a promising source of natural products with potential antimicrobial activity.
为了寻找新的生物活性天然产物，对从阿尔及利亚药用芳香植物刺芹（Daucus muricatus L.）分离器官中提取的精油成分的抗菌和抗氧化活性进行了研究。
采用气相色谱 - 保留指数（GC - RI）和气相色谱 - 质谱联用（GC - MS）对水蒸馏法（HD）获得的精油化学成分进行了研究。刺芹产生两种类型的精油：（i）根部精油主要由非萜类含氧化合物组成（59.8 g/100 g），（ii）地上部分精油（即叶、茎、花和伞形花序）主要由萜类碳氢化合物组成（62.3 - 72.2 g/100 g）。在优化固相微萃取参数后，通过顶空固相微萃取/气相色谱 - 保留指数（HS - SPME/GC - RI）和气相色谱 - 质谱联用（GC - MS）研究了从刺芹不同器官分离的挥发性成分的化学成分。对于所有研究的器官，该植物释放的主要挥发性物质是碳氢化合物（60.7 - 82.2 g/100 g）。仅观察到所研究的分离器官挥发性成分之间的定量差异。此外，还研究了刺芹精油对八种细菌菌株和一种酵母菌的活性。根部精油对金黄色葡萄球菌有活性，而从地上部分获得的精油对白色念珠菌有活性。
刺芹精油似乎是具有潜在抗菌活性的天然产物的有前途来源。
