BioSciences Institute, University College Cork, Cork, Ireland.
Virol J. 2010 Jan 25;7:17. doi: 10.1186/1743-422X-7-17.
Overlapping genes are common in RNA viruses where they serve as a mechanism to optimize the coding potential of compact genomes. However, annotation of overlapping genes can be difficult using conventional gene-finding software. Recently we have been using a number of complementary approaches to systematically identify previously undetected overlapping genes in RNA virus genomes. In this article we gather together a number of promising candidate new overlapping genes that may be of interest to the community.
Overlapping gene predictions are presented for the astroviruses, seadornaviruses, cytorhabdoviruses and coronaviruses (families Astroviridae, Reoviridae, Rhabdoviridae and Coronaviridae, respectively).
重叠基因在 RNA 病毒中很常见，它们是优化紧凑基因组编码潜力的一种机制。然而，使用传统的基因发现软件对重叠基因进行注释可能很困难。最近，我们一直在使用多种互补的方法来系统地识别 RNA 病毒基因组中以前未检测到的重叠基因。在本文中，我们汇集了一些有希望的候选新重叠基因，这些基因可能引起社区的兴趣。
分别为星状病毒、海德尔堡病毒、细胞弹状病毒和冠状病毒（分别为星状病毒科、呼肠孤病毒科、弹状病毒科和冠状病毒科）预测了重叠基因。
