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哺乳动物和禽星状病毒的广泛宿主范围及遗传多样性

The Broad Host Range and Genetic Diversity of Mammalian and Avian Astroviruses.

作者信息

Donato Celeste, Vijaykrishna Dhanasekaran

机构信息

Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia.

Duke-NUS Medical School, Singapore 169857, Singapore.

出版信息

Viruses. 2017 May 10;9(5):102. doi: 10.3390/v9050102.

Abstract

Astroviruses are a diverse family of viruses that infect a wide range of mammalian and avian hosts. Here we describe the phylogenetic diversity and current classification methodology of astroviruses based on the ORF1b and ORF2 genes, highlighting the propensity of astroviruses to undergo interspecies transmission and genetic recombination which greatly increase diversity and complicate attempts at a unified and comprehensive classification strategy.

摘要

星状病毒是一类多样的病毒,可感染多种哺乳动物和鸟类宿主。在此,我们基于ORF1b和ORF2基因描述了星状病毒的系统发育多样性和当前分类方法,强调了星状病毒进行种间传播和基因重组的倾向,这大大增加了多样性,并使统一和全面的分类策略复杂化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eef/5454415/11bcc69814ff/viruses-09-00102-g001.jpg

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