Yilmaz Ozlem, Turgay Nevin
Ege Universitesi Tip Fakültesi, Fizyoloji Anabilim Dali, Izmir, Turkey.
Turkiye Parazitol Derg. 2009;33(4):301-6.
Parasitic diseases have worldwide medical and economical consequences. A variety of parasite and host factors such as host T lymphocytes and cytokines have a strong impact on the outcome of parasitic infections. In this review we discussed how negative regulatory mechanisms of cytokine related intracellular signals attenuation are essential for ensuring and appropriate, controlled cellular immune response on parasitic infections.
寄生虫病在全球范围内都具有医学和经济影响。多种寄生虫和宿主因素,如宿主T淋巴细胞和细胞因子,对寄生虫感染的结果有很大影响。在本综述中,我们讨论了细胞因子相关细胞内信号衰减的负调控机制对于确保对寄生虫感染产生适当、可控的细胞免疫反应至关重要。