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本文引用的文献

1
Long-term outcomes of laparoscopic Heller myotomy for achalasia.贲门失弛缓症腹腔镜下Heller肌切开术的长期疗效
Surgery. 2009 Oct;146(4):826-31; discussion 831-3. doi: 10.1016/j.surg.2009.06.049.
2
Delayed presentation of intrathoracic esophageal perforation after pneumatic dilation for achalasia.贲门失弛缓症行气囊扩张后发生的迟发性胸腔内食管穿孔。
World J Gastroenterol. 2009 Sep 21;15(35):4461-3. doi: 10.3748/wjg.15.4461.
3
Current clinical approach to achalasia.贲门失弛缓症的当前临床治疗方法。
World J Gastroenterol. 2009 Aug 28;15(32):3969-75. doi: 10.3748/wjg.15.3969.
4
Education and Imaging. Gastrointestinal: pseudoachalasia caused by a lower esophageal stromal tumor.教育与影像。胃肠道:由食管下段间质瘤引起的假性贲门失弛缓症。
J Gastroenterol Hepatol. 2009 Jun;24(6):1152. doi: 10.1111/j.1440-1746.2009.05883.x.
5
Laparoscopic diagnosis of pleural mesothelioma presenting with pseudoachalasia.腹腔镜诊断表现为假性贲门失弛缓症的胸膜间皮瘤。
World J Gastroenterol. 2009 Jul 28;15(28):3569-72. doi: 10.3748/wjg.15.3569.
6
Laparoscopic Heller myotomy for achalasia: results after 10 years.腹腔镜 Heller 肌切开术治疗贲门失弛缓症:10 年后的结果。
Surg Endosc. 2009 Dec;23(12):2644-9. doi: 10.1007/s00464-009-0508-1. Epub 2009 Jun 24.
7
Long-term clinical outcome after botulinum toxin injection in children with nonrelaxing internal anal sphincter.肉毒杆菌毒素注射治疗儿童肛门内括约肌不松弛的长期临床疗效。
Am J Gastroenterol. 2009 Apr;104(4):976-83. doi: 10.1038/ajg.2008.110. Epub 2009 Mar 3.
8
Achalasia of the esophagus: a surgical disease.食管贲门失弛缓症:一种外科疾病。
J Am Coll Surg. 2009 Jan;208(1):151-62. doi: 10.1016/j.jamcollsurg.2008.08.027. Epub 2008 Oct 2.
9
Clinical remission in endoscope-guided pneumatic dilation for the treatment of esophageal achalasia: 7-year follow-up results of a prospective investigation.内镜引导下气囊扩张治疗贲门失弛缓症的临床缓解:一项前瞻性研究的7年随访结果
J Gastrointest Surg. 2009 May;13(5):862-7. doi: 10.1007/s11605-009-0804-z. Epub 2009 Jan 23.
10
Meta-analysis of randomized and controlled treatment trials for achalasia.贲门失弛缓症随机对照治疗试验的荟萃分析。
Dig Dis Sci. 2009 Nov;54(11):2303-11. doi: 10.1007/s10620-008-0637-8. Epub 2008 Dec 24.

内镜引导下气囊扩张治疗食管失弛缓症。

Endoscope-guided pneumatic dilation for treatment of esophageal achalasia.

出版信息

World J Gastroenterol. 2010 Jan 28;16(4):411-7. doi: 10.3748/wjg.v16.i4.411.

DOI:10.3748/wjg.v16.i4.411
PMID:20101764
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2811791/
Abstract

Pneumatic dilation (PD) is considered to be the first line nonsurgical therapy for achalasia. The principle of the procedure is to weaken the lower esophageal sphincter by tearing its muscle fibers by generating radial force. The endoscope-guided procedure is done without fluoroscopic control. Clinicians usually use a low-compliance balloon such as Rigiflex dilator to perform endoscope-guided PD for the treatment of esophageal achalasia. It has the advantage of determining mucosal injury during the dilation process, so that a repeat endoscopy is not needed to assess the mucosal tearing. Previous studies have shown that endoscope-guided PD is an efficient and safe nonsurgical therapy with results that compare well with other treatment modalities. Although the results may be promising, long-term follow-up is required in the near future.

摘要

气动扩张术(PD)被认为是治疗贲门失弛缓症的一线非手术治疗方法。该手术的原理是通过产生径向力撕裂下食管括约肌的肌肉纤维来减弱其张力。该内镜引导下的手术无需荧光透视控制。临床医生通常使用低顺应性球囊(如 Rigiflex 扩张器)来进行内镜引导下 PD 治疗食管失弛缓症。它的优点是可以在扩张过程中确定黏膜损伤,因此无需再次进行内镜检查来评估黏膜撕裂情况。先前的研究表明,内镜引导 PD 是一种有效且安全的非手术治疗方法,其效果与其他治疗方式相当。尽管结果可能很有前景,但在不久的将来仍需要进行长期随访。