Wang Bin, Xu Yin-Feng, Li Guo-Qiang, Guan Hua-Shi
School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316000, China.
Guang Pu Xue Yu Guang Pu Fen Xi. 2009 Nov;29(11):3138-40.
An inductively coupled plasma mass spectrometry (ICP-MS) for determination of the contents of 27 inorganic elements in Limonium bicolor after microwave digestion of the sample was developed. The accuracy of the method was evaluated by the analysis of corresponding inorganic elements in standard reference materials (GBW 07605), and matrix effect and signal drift were compensated by using the internal standard elements (Ge, In and Bi). By applying the proposed method, the contents of 27 inorganic elements in Limonium bicolor collected from Dongying (Shandong Province of China) were determined. The precision of measurement ranges from 1.5% to 9.7% in terms of relative standard deviation. The recoveries and the limits of detection are in the range of 92.4%-107.2% and 0.002-0.081 microg x L(-1), respectively. It is indicated that the proposed method has the advantages of simplicity, speediness and sensitivity. The results showed that the Limonium bicolor are rich in major elements Na, K, Ca and Mg and trace elements Fe, Mn, Zn, Cr and Cu. This paper provides scientific basis for deeply studying the relation between the inorganic elements and the drug effects of Limonium bicolor.
建立了一种电感耦合等离子体质谱法（ICP-MS），用于测定样品经微波消解后的二色补血草中27种无机元素的含量。通过分析标准参考物质（GBW 07605）中的相应无机元素来评估该方法的准确性，并使用内标元素（Ge、In和Bi）补偿基体效应和信号漂移。应用该方法测定了采自中国山东省东营市的二色补血草中27种无机元素的含量。测量精密度以相对标准偏差计在1.5%至9.7%之间。回收率和检测限分别在92.4% - 107.2%和0.002 - 0.081 μg·L⁻¹范围内。结果表明该方法具有简便、快速和灵敏的优点。结果显示，二色补血草富含常量元素Na、K、Ca和Mg以及微量元素Fe、Mn、Zn、Cr和Cu。本文为深入研究二色补血草中无机元素与药效之间的关系提供了科学依据。
