Segregur Jadranko, Buković Damir, Milinović Darko, Oresković Slavko, Pavelić Jasminka, Zupić Tomislav, Persec Jasminka, Pavić Mato
Department of Gynecology and Obstetrics, General Hospital Virovitica, Virovitica, Croatia.
Coll Antropol. 2009 Dec;33(4):1121-7.
The aim of the study was to determine the frequency of fetal macrosomia in newborns from mothers with gestational diabetes mellitus (GDM) and healthy mothers, as well as determining the influence of fetal growth on pregnancy termination, on complications in pregnancy, during delivery and puerperium and on neonatal complications. In the study were included 351 pregnant women with GDM, as well as control group of 1502 healthy pregnant women. Newborns of mothers with GDM had significantly higher birth weight and length, ponderal index > 2.85 was more frequent, they were macrosomic and hypertrophic (disproportional and proportional), had smaller Apgar score and more frequent neonatal complications (p < 0.05). Fetal macrosomia and fetal hypertrophy alone or, particularly, connected with disproportional fetal growth, but disproportional hypotrophy as well, had significantly influence on greater frequency of delivery and puerperal complications, delivery completion with Cesarean section and neonatal complications in pregnant women with GDM.
该研究的目的是确定患有妊娠期糖尿病(GDM)的母亲和健康母亲所生新生儿中巨大儿的发生率,以及确定胎儿生长对妊娠终止、孕期并发症、分娩期及产褥期并发症以及新生儿并发症的影响。该研究纳入了351例患有GDM的孕妇以及1502例健康孕妇作为对照组。患有GDM的母亲所生新生儿的出生体重和身长显著更高,体重指数>2.85更为常见,他们为巨大儿且有肥大现象(不成比例和成比例),阿氏评分较低且新生儿并发症更常见(p<0.05)。单纯的胎儿巨大和胎儿肥大,尤其是与不成比例的胎儿生长相关,但不成比例的发育不良也一样,对患有GDM的孕妇分娩和产褥期并发症的发生率更高、剖宫产完成分娩以及新生儿并发症有显著影响。