Center for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA.
Addiction. 2010 Apr;105(4):626-36. doi: 10.1111/j.1360-0443.2009.02820.x. Epub 2010 Jan 22.
Indices of negative affect, such as depression, have been implicated in stress-induced pathways to alcohol relapse. Empirically supported continuing care resources, such as Alcoholics Anonymous (AA), emphasize reducing negative affect to reduce relapse risk, but little research has been conducted to examine putative affective mechanisms of AA's effects.
Using lagged, controlled, hierarchical linear modeling and mediational analyses this study investigated whether AA participation mobilized changes in depression symptoms and whether such changes explained subsequent reductions in alcohol use. Alcohol-dependent adults (n = 1706), receiving treatment as part of a clinical trial, were assessed at intake, 3, 6, 9, 12 and 15 months.
Findings revealed elevated levels of depression compared to the general population, which decreased during treatment and then remained stable over follow-up. Greater AA attendance was associated with better subsequent alcohol use outcomes and decreased depression. Greater depression was associated with heavier and more frequent drinking. Lagged mediation analyses revealed that the effects of AA on alcohol use was mediated partially by reductions in depression symptoms. However, this salutary effect on depression itself appeared to be explained by AA's proximal effect on reducing concurrent drinking.
AA attendance was associated both concurrently and predictively with improved alcohol outcomes. Although AA attendance was associated additionally with subsequent improvements in depression, it did not predict such improvements over and above concurrent alcohol use. AA appears to lead both to improvements in alcohol use and psychological and emotional wellbeing which, in turn, may reinforce further abstinence and recovery-related change.
负面情绪指数,如抑郁,与压力导致的酒精复发途径有关。实证支持的持续护理资源,如匿名戒酒会(AA),强调减少负面情绪以降低复发风险,但很少有研究探讨 AA 效果的潜在情感机制。
本研究使用滞后、对照、分层线性建模和中介分析,调查了 AA 参与是否调动了抑郁症状的变化,以及这些变化是否解释了随后饮酒量的减少。接受治疗作为临床试验一部分的酒精依赖成年人(n = 1706)在入组时、3 个月、6 个月、9 个月、12 个月和 15 个月进行评估。
研究结果显示,与一般人群相比,参与者的抑郁水平较高,在治疗期间下降,随后在随访期间保持稳定。AA 出勤率较高与随后更好的酒精使用结果和降低的抑郁有关。较高的抑郁与更频繁、更频繁的饮酒有关。滞后中介分析显示,AA 对饮酒的影响部分通过抑郁症状的减轻来介导。然而,这种对抑郁的有益影响本身似乎可以用 AA 对减少同时饮酒的直接影响来解释。
AA 出勤率与改善酒精结果既相关又有预测性。尽管 AA 出勤率与随后的抑郁改善有关,但它并不能预测这种改善超过同期的饮酒量。AA 似乎既可以改善酒精使用,也可以改善心理和情绪健康,这反过来又可能加强进一步的禁欲和与康复相关的变化。