Department of Epidemiology and Public Health, Imperial College London, UK.
Environ Health. 2009 Dec 21;8 Suppl 1(Suppl 1):S7. doi: 10.1186/1476-069X-8-S1-S7.
Studies of disinfection by-products in drinking water and measures of adverse fetal growth have often been limited by exposure assessment lacking data on individual water use, and therefore failing to reflect individual variation in DBP exposure.
Pregnant women recruited to the Born in Bradford cohort study completed a questionnaire which covers water exposure. Information was collected on water consumption, showering, bathing and swimming. Water exposure data from a subset of 39 women of the cohort are described here.
Mean total tap water intake was 1.8 l/day, and women on average spent 146 minutes per week showering and bathing. Most tap water intake occurred at home (100% for unemployed, 71.8% for employed). Differences between age groups were observed for total tap water intake overall (p = 0.02) and at home (p = 0.01), and for bottled water intake (p = 0.05). There were differences between ethnic groups for tap water intake at home (p = 0.02) and total tap water intake at work (p = 0.02). Total tap water intake at work differed by income category (p = 0.001). Duration per shower was inversely correlated with age (Spearman's correlation -0.39, p = 0.02), and differed according to employment status (p = 0.04), ethnicity (p = 0.02) and income (p = 0.02).
This study provides estimates of water exposure in pregnant women in a multi-ethnic population in the north of England and suggests differences related to age, employment, income and ethnicity. The findings are valuable to inform exposure assessment in studies assessing the relationship between DBPs and adverse birth outcomes.
饮用水中消毒副产物的研究以及对胎儿生长不良的测量,通常受到缺乏个体用水暴露数据的影响,因此无法反映出个体中消毒副产物的暴露差异。
参与布拉德福德出生队列研究的孕妇完成了一份涵盖水暴露的调查问卷。收集了关于水消耗、淋浴、洗澡和游泳的信息。本研究介绍了该队列中 39 名女性的子集中的水暴露数据。
平均总自来水摄入量为 1.8 升/天,女性平均每周淋浴和洗澡 146 分钟。自来水的摄入主要发生在家里(失业者为 100%,就业者为 71.8%)。总体而言,不同年龄组的自来水总摄入量(p=0.02)和家庭摄入量(p=0.01)以及瓶装水摄入量(p=0.05)存在差异。不同种族群体在家中自来水摄入量(p=0.02)和工作场所自来水总摄入量(p=0.02)方面存在差异。工作场所自来水总摄入量因收入类别而异(p=0.001)。每次淋浴的时间与年龄呈负相关(Spearman 相关系数-0.39,p=0.02),且因就业状况(p=0.04)、种族(p=0.02)和收入(p=0.02)而异。
本研究提供了英格兰北部多民族人群中孕妇水暴露的估计值,并表明与年龄、就业、收入和种族有关的差异。这些发现对于告知评估消毒副产物与不良出生结局之间关系的研究中的暴露评估具有重要意义。