Department of Veterans Affairs, Health Services Research and Development (HSR&D), Center of Excellence, Serious Mental Illness Treatment Research and Evaluation Center (SMITREC), Ann Arbor, MI, USA.
Am J Geriatr Psychiatry. 2009 Dec;17(12):1068-76. doi: 10.1097/JGP.0b013e3181b972d1.
Cost-related medication nonadherence (CRN) was problematic for Medicare beneficiaries with depressive symptoms before Medicare Part D.
To estimate changes in CRN and forgoing basic needs to pay for drugs among Medicare beneficiaries with and without depressive symptoms following Part D implementation.
The authors compared changes in outcomes between 2005 and 2006 before and after Part D with changes between 2004 and 2005 using logistic regression to control for demographic characteristics, health status, and historical trends.
The community-dwelling sample of the Medicare Current Beneficiary Survey (N = 24,234).
Self-reports of CRN (skipping or reducing doses and not obtaining prescriptions) and spending less on basic needs to afford medicines.
The unadjusted annual prevalence of CRN among beneficiaries with depressive symptoms was 27% (2004), 27% (2005), and 24% (2006), compared with 13%, 12%, and 9% among beneficiaries without depressive symptoms. The annual prevalence of spending less on basic needs was 22% (2004), 23% (2005), and 19% (2006), compared with 8%, 9%, and 5% among beneficiaries without depressive symptoms. Controlling for historical changes and demographic characteristics, CRN did not decline among beneficiaries with depressive symptoms compared with beneficiaries without depressive symptoms (ratio of Part D changes 0.98; 95% confidence interval [CI], 0.73-1.32). Respondents with depressive symptoms seemed less likely to spend less on basic needs compared with individuals without depressive symptoms (0.70; 95% CI, 0.49-1.01); however, this difference was not statistically significant.
Despite a Medicare Part D goal to improve medication adherence among mentally ill beneficiaries, the disparity in economic access to medications between beneficiaries with and without depressive symptoms did not improve after the start of Part D.
在医疗保险处方药计划(Medicare Part D)实施之前,有抑郁症状的医疗保险受益人群存在与费用相关的药物不依从(CRN)问题。
评估医疗保险受益人群在实施医疗保险处方药计划后,有抑郁症状和无抑郁症状人群的 CRN 及为支付药物费用而放弃基本需求的情况变化。
作者使用逻辑回归比较了医疗保险受益人群在实施医疗保险处方药计划前后(2005 年和 2006 年)与实施前一年(2004 年和 2005 年)之间结果的变化,控制了人口统计学特征、健康状况和历史趋势。
医疗保险当前受益人群调查(Medicare Current Beneficiary Survey)的社区居住样本(N=24234)。
自我报告的 CRN(减少剂量或不服用药物以及未获取处方)和为支付药物费用而减少基本需求的支出。
有抑郁症状的受益人群未经调整的年度 CRN 发生率为 27%(2004 年)、27%(2005 年)和 24%(2006 年),而无抑郁症状的受益人群为 13%、12%和 9%。有抑郁症状的受益人群年度减少基本需求支出的发生率为 22%(2004 年)、23%(2005 年)和 19%(2006 年),而无抑郁症状的受益人群为 8%、9%和 5%。在控制历史变化和人口统计学特征后,有抑郁症状的受益人群与无抑郁症状的受益人群相比,CRN 并没有下降(医疗保险处方药计划变化的比值为 0.98;95%置信区间[CI],0.73-1.32)。与没有抑郁症状的个体相比,有抑郁症状的受访者似乎不太可能减少基本需求的支出(0.70;95%CI,0.49-1.01);然而,这种差异在统计学上并不显著。
尽管医疗保险处方药计划的目标是改善精神病受益人群的药物依从性,但在该计划开始后,有抑郁症状和无抑郁症状的受益人群在获得药物方面的经济差距并没有缩小。