Boston Medical Center, Section of Gastroenterology, Department of Gastroenterology, Boston University School of Medicine, Boston, Massachusetts 02118, USA.
Am J Gastroenterol. 2010 Jun;105(6):1231-8. doi: 10.1038/ajg.2009.733. Epub 2010 Jan 26.
The increasing use of corticosteroids, immune modulators, and biologics as a mainstay of therapy in certain Crohn's disease and ulcerative colitis patients have placed these inflammatory bowel disease (IBD) patients at increased risk for a variety of infections, many of which are preventable by prior vaccination. This article provides a review of the issues surrounding immunizations in the IBD patient and a practical guide for clinicians regarding the appropriate vaccinations to administer both before and during immunosuppressive therapy.
由于某些克罗恩病和溃疡性结肠炎患者将皮质类固醇、免疫调节剂和生物制剂作为主要治疗方法，这些炎症性肠病（IBD）患者面临多种感染的风险增加，其中许多感染可以通过预先接种疫苗来预防。本文综述了 IBD 患者免疫接种的相关问题，并为临床医生提供了关于在免疫抑制治疗前后给予适当疫苗接种的实用指南。
