Internal Medicine, University of Manitoba, 805-715 McDermot Avenue, Winnipeg, Manitoba R3E3P4, Canada.
Am J Gastroenterol. 2010 Jul;105(7):1541-50. doi: 10.1038/ajg.2009.756. Epub 2010 Jan 26.
We sought to conduct an assessment of the practice of gastrostomy (G) tube placement across an entire city, which would reflect usual clinical care as compared with referral center practice.
We reviewed and retrospectively extracted data from patient records for all percutaneous endoscopic G (PEG) and radiological percutaneous G (RPG) tube placements at six Winnipeg hospitals between 1 April 2005 and 31 March 2007.
A total of 418 patients had G tubes (376 PEG, 42 RPG) inserted during the study period. The most common indications were cerebrovascular accidents (25%), head and neck cancer (23%), and head trauma (10%). The position of the external bolster was not documented in 38% of patients. The median time to the first complication was 10 days, initiation of feeding was 48 hours, and tube removal was 40 days. Complications developed in 102 (24%) patients. Patients with RPG tubes had more infections and were less likely to receive prophylactic antibiotics (P<0.001). In multivariate analysis, complications were more likely to occur in patients with RPG tubes and after insertions by lowest procedure volume physicians. Overall mortality was 12% within 30 days of G-tube placement. Death of one patient was directly related to peritonitis after G-tube insertion.
In usual clinical practice, there is an underuse of prophylactic antibiotics and a delay in the institution of nutritional support after G-tube placement. A small but significant proportion of patients may develop major complications, with associated risk of mortality. The higher complication rate after procedures performed by lowest volume physicians needs further evaluation.
我们旨在评估整个城市的胃造口术(G)管放置实践,以反映与转诊中心实践相比的常规临床护理。
我们回顾并从 2005 年 4 月 1 日至 2007 年 3 月 31 日期间在温尼伯的六家医院的所有经皮内镜胃(PEG)和放射经皮胃(RPG)管放置患者记录中提取数据。
研究期间共 418 例患者插入 G 管(376 例 PEG,42 例 RPG)。最常见的适应症是脑血管意外(25%),头颈部癌(23%)和头部创伤(10%)。38%的患者未记录外部支撑垫的位置。首次并发症的中位时间为 10 天,开始喂养的时间为 48 小时,管移除的时间为 40 天。102 例(24%)患者发生并发症。RPG 管患者发生感染的可能性更高,且更不可能接受预防性抗生素治疗(P<0.001)。在多变量分析中,RPG 管和最低程序量医生进行的插入术更容易发生并发症。在 G 管放置后 30 天内的总死亡率为 12%。一名患者的死亡与 G 管插入后腹膜炎直接相关。
在常规临床实践中,预防性抗生素的使用不足且在 G 管放置后营养支持的启动延迟。一小部分患者可能会发生严重并发症,且相关死亡率较高。由最低量医生进行的程序的更高并发症率需要进一步评估。