龙眼（Dimocarpus longan Lour.）种籽多糖抗疲劳作用的初步观察。
Preliminary observations on the antifatigue effects of longan (Dimocarpus longan Lour.) seed polysaccharides.
机构信息
Fujian Fruit Breeding Engineering Technology Research Center for Longan and Loquat, Fuzhou, Fujian 350013, China.
出版信息
Phytother Res. 2010 Apr;24(4):622-4. doi: 10.1002/ptr.2963.
The antifatigue effects of the hot-water extract of longan (Dimocarpus longan Lour.) seeds were studied in mice. Longan seed polysaccharides were administered at doses of 50, 100, 200 and 400 mg/kg and antifatigue activity was evaluated using a swimming test, along with the determination of serum urea nitrogen, hepatic glycogen and blood lactic acid content. The results show that longan seed polysaccharides, in doses ranging from 50 to 100 mg/kg, extended swimming time, increased hepatic glycogen (p < 0.01, n = 10), reduced blood urea nitrogen (p < 0.01, n = 10) and decreased blood lactic acid (p < 0.01, n = 10) in the mice. Therefore longan seed polysaccharides may have potential as an antifatigue agent.
研究了龙眼（Dimocarpus longan Lour.）种子热水提取物的抗疲劳作用。龙眼籽多糖以 50、100、200 和 400 mg/kg 的剂量给药，并通过游泳试验评估抗疲劳活性，同时测定血清尿素氮、肝糖原和血液中乳酸的含量。结果表明，龙眼籽多糖在 50 至 100 mg/kg 的剂量范围内可延长游泳时间，增加肝糖原（p<0.01，n=10），降低血清尿素氮（p<0.01，n=10）并降低血液中的乳酸（p<0.01，n=10）。因此，龙眼籽多糖可能具有作为抗疲劳剂的潜力。
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