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用于疾病传播的 SIS 反应扩散传染病模型的动力学。

Dynamics of an SIS reaction-diffusion epidemic model for disease transmission.

机构信息

Department of Mathematics, Shanghai Normal University, Shanghai, 200234, China.

出版信息

Math Biosci Eng. 2010 Jan;7(1):51-66. doi: 10.3934/mbe.2010.7.51.

Abstract

Recently an SIS epidemic reaction-diffusion model with Neumann (or no-flux) boundary condition has been proposed and studied by several authors to understand the dynamics of disease transmission in a spatially heterogeneous environment in which the individuals are subject to a random movement. Many important and interesting properties have been obtained: such as the role of diffusion coefficients in defining the reproductive number; the global stability of disease-free equilibrium; the existence and uniqueness of a positive endemic steady; global stability of endemic steady for some particular cases; and the asymptotical profiles of the endemic steady states as the diffusion coefficient for susceptible individuals is sufficiently small. In this research we will study two modified SIS diffusion models with the Dirichlet boundary condition that reflects a hostile environment in the boundary. The reproductive number is defined which plays an essential role in determining whether the disease will extinct or persist. We have showed that the disease will die out when the reproductive number is less than one and that the endemic equilibrium occurs when the reproductive number is exceeds one. Partial result on the global stability of the endemic equilibrium is also obtained.

摘要

最近,一些作者提出并研究了一个具有 Neuman(或无通量)边界条件的 SIS 传染病扩散模型,以了解在个体受到随机运动的空间异质环境中疾病传播的动态。已经获得了许多重要和有趣的性质:例如扩散系数在定义繁殖数中的作用;无病平衡点的全局稳定性;正地方病平衡点的存在性和唯一性;在某些特定情况下地方病平衡点的全局稳定性;以及当易感个体的扩散系数足够小时地方病平衡点的渐近轮廓。在这项研究中,我们将研究两个具有 Dirichlet 边界条件的修正 SIS 扩散模型,该边界条件反映了边界处的敌对环境。定义了繁殖数,它在确定疾病是否会灭绝或持续存在方面起着至关重要的作用。我们已经表明,当繁殖数小于一时,疾病就会消亡,当繁殖数大于一时,地方病平衡点就会发生。还得到了地方病平衡点全局稳定性的部分结果。

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