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具有非线性发病率的传染病模型的全局性质

Global properties of infectious disease models with nonlinear incidence.

作者信息

Korobeinikov Andrei

机构信息

Laboratory of Nonlinear Science and Computation, Research Institute for Electronic Science, Hokkaido University, Sapporo, 060-0812, Japan.

出版信息

Bull Math Biol. 2007 Aug;69(6):1871-86. doi: 10.1007/s11538-007-9196-y. Epub 2007 Apr 19.

Abstract

We consider global properties for the classical SIR, SIRS and SEIR models of infectious diseases, including the models with the vertical transmission, assuming that the horizontal transmission is governed by an unspecified function f(S,I). We construct Lyapunov functions which enable us to find biologically realistic conditions sufficient to ensure existence and uniqueness of a globally asymptotically stable equilibrium state. This state can be either endemic, or infection-free, depending on the value of the basic reproduction number.

摘要

我们考虑经典的传染病SIR、SIRS和SEIR模型的全局性质,包括具有垂直传播的模型,假设水平传播由一个未指定的函数f(S, I)控制。我们构造李雅普诺夫函数,这使我们能够找到足以确保全局渐近稳定平衡态存在且唯一的生物学现实条件。根据基本再生数的值,这个状态可以是地方病状态,也可以是无感染状态。

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