Department of Community Health and Epidemiology, Queen's University, Kingston, ON, Canada.
Acta Psychiatr Scand. 2010 May;121(5):325-39. doi: 10.1111/j.1600-0447.2009.01535.x. Epub 2010 Jan 25.
Compare the risk for schizophrenia in immigrants to countries of recent and longstanding immigration. Compare prevalence and incidence rates in black subjects under different conditions.
An electronic literature search was complemented by review articles and cross-references. Studies reporting standard diagnosis and incidence or prevalence rates were included.
Immigrants had an increased risk for schizophrenia in countries of longstanding immigration, but with lower risk ratios than in those of recent immigration. The risk was higher in black immigrants and the black population living in the United States. But incidence and prevalence rates in Africa and the Caribbean were similar to those of international studies.
Comparing the most recent generation of immigrants with descendants of previous ones may account for the lower risk ratios observed in countries of longstanding vs. recent immigration. Two neurobiological hypotheses are proposed to explain the epidemiological findings in black populations and in immigrants.
比较近期移民和长期移民国家移民的精神分裂症发病风险。比较不同情况下黑人患者的患病率和发病率。
电子文献检索辅以综述文章和交叉引用。纳入报告标准诊断和发病率或患病率的研究。
在长期移民国家，移民精神分裂症发病风险增加，但风险比低于近期移民国家。黑人移民和生活在美国的黑人人口风险更高。但是，非洲和加勒比地区的发病率和患病率与国际研究相似。
与长期移民国家相比，近期移民国家观察到的风险比更低，这可能与比较最新一代移民和前几代移民有关。提出了两个神经生物学假设来解释黑人人群和移民中的流行病学发现。
