[由于致癌物的同时作用导致小鼠和大鼠肝脏中的抗原重排]
[Antigenic rearrangement in the liver of mice and rats as a result of simultaneous effect of the carcinogens].
作者信息
Ivanov V A, Avertsev S A, Fel' V Ia, Olenov Iu M
出版信息
Tsitologiia. 1977 Jul;19(7):781-5.
PMID:201056
Abstract
The antigenic structure of the livers of mice and rats after a single hepatocarcinogenic treatment was investigated using the immunodiffuse and immunofluorescent methods. The next day after carcinogen application changes characteristic of hepatocellular tumors were observed: decrease in the synthesis of organospecific antigens and intensification of the synthesis of heteroorganic antigens.
摘要
采用免疫扩散和免疫荧光法研究了小鼠和大鼠单次肝癌致癌处理后肝脏的抗原结构。在施用致癌物后的第二天，观察到肝细胞肿瘤的特征性变化：器官特异性抗原合成减少，异种有机抗原合成增强。
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