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职场及社区环境中的胆固醇降低

Cholesterol reduction in the workplace and in community settings.

作者信息

Wilson M G

机构信息

Department of Health Promotion & Behavior, University of Georgia, Athens 30602.

出版信息

J Community Health. 1991 Feb;16(1):49-65. doi: 10.1007/BF01340468.

Abstract

Recent emphasis has been placed on the role of serum cholesterol in the development of cardiovascular disease and on reducing high serum cholesterol levels through a screening followed by a behavioral intervention. However, evidence about the effectiveness of this technique in reducing cholesterol has yet to be evaluated. A review of the biomedical and allied health literature was conducted to determine the effectiveness of reducing serum cholesterol levels in the general population through the use of a screening to identify those at risk followed by a behavioral intervention. Only worksite and community based studies published from 1980-89 were reviewed. Seven worksite and four community studies were identified. All studies used total serum cholesterol as the dependent variable while some included other physiological measures. The majority of studies used a multicomponent intervention involving dietary education, exercise, smoking cessation, or weight reduction components. The interventions tested lasted from 14 weeks to five years and varied from low intensity to high intensity. The methods of intervention ranged from face-to-face interaction to mail and telephone counseling. Although many of the studies reviewed contain methodological flaws, certain findings are evident. The studies show that cholesterol can be reduced through a screening followed by a behavioral intervention, the multicomponent program is the most effective intervention, and low intensive interventions are as equally effective as high intensive interventions. Program implications and future research directions are discussed.

摘要

近期,人们一直强调血清胆固醇在心血管疾病发展中的作用,以及通过筛查后进行行为干预来降低高血清胆固醇水平。然而,关于该技术降低胆固醇有效性的证据尚未得到评估。我们对生物医学及相关健康文献进行了综述,以确定通过筛查识别高危人群后进行行为干预,在普通人群中降低血清胆固醇水平的有效性。仅对1980年至1989年发表的工作场所和社区研究进行了综述。确定了七项工作场所研究和四项社区研究。所有研究均将血清总胆固醇作为因变量,一些研究还纳入了其他生理指标。大多数研究采用了多成分干预措施,包括饮食教育、运动、戒烟或减重等成分。所测试的干预措施持续时间从14周至五年不等,强度从低到高各不相同。干预方法从面对面互动到邮件和电话咨询。尽管许多综述研究存在方法学缺陷,但某些发现是明显的。这些研究表明,通过筛查后进行行为干预可以降低胆固醇,多成分项目是最有效的干预措施,低强度干预与高强度干预同样有效。文中还讨论了项目的意义和未来研究方向。

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