Reid D W, Tierney M C, Zorzitto M L, Snow W G, Fisher R H
Department of Psychology, York University, Toronto, Ontario, Canada.
J Am Geriatr Soc. 1991 Apr;39(4):368-71. doi: 10.1111/j.1532-5415.1991.tb02901.x.
The London Psychogeriatric Rating Scale (LPRS) was administered to 76 probable Alzheimer's patients, 59 patients with dementia unrelated to Alzheimer's, 102 neurologically normal subjects, and 27 patients with symptoms of both Alzheimer's and dementia of other etiologies. By examining the relationships among the four subscales of the LPRS and conducting factor analyses, it was demonstrated that the four subscales were not measuring different phenomena. The internal consistency of the full 36-item scale was high (Cronbach's Alpha = 0.96) indicating the total LPRS score provided a reliable global index of behavioral function. The total LPRS scores correlated with the independently administered Goldfarb Mental Status Examination scores (r = -0.79). The LPRS differentiated between the normals and the combined demented groups and between inpatients and outpatients. The LPRS continues to have clinical value for functional assessments in a non-intrusive manner. The LPRS may be particularly useful in situations where direct assessment of mental status is not practical.
对76例疑似阿尔茨海默病患者、59例与阿尔茨海默病无关的痴呆患者、102例神经功能正常的受试者以及27例同时患有阿尔茨海默病和其他病因所致痴呆症状的患者进行了伦敦老年精神病评定量表(LPRS)评估。通过检查LPRS四个分量表之间的关系并进行因子分析,结果表明这四个分量表并未测量不同的现象。整个36项量表的内部一致性较高(克朗巴赫α系数 = 0.96),表明LPRS总分提供了一个可靠的行为功能整体指标。LPRS总分与独立进行的戈德法布精神状态检查得分相关(r = -0.79)。LPRS能够区分正常组与合并痴呆组,以及住院患者和门诊患者。LPRS继续以非侵入性方式在功能评估中具有临床价值。在无法实际进行精神状态直接评估的情况下,LPRS可能特别有用。