整体和单分子 FRET 分析 c-kit 启动子四联体的结构和展开动力学。
Ensemble and single molecule FRET analysis of the structure and unfolding kinetics of the c-kit promoter quadruplexes.
机构信息
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UKCB2 1EW.
出版信息
Chem Commun (Camb). 2010 Feb 14;46(6):946-8. doi: 10.1039/b920680a. Epub 2009 Dec 10.
Abstract
FRET analysis has been used to examine the folded conformations and differing kinetic stabilities of two DNA G-quadruplexes (c-kit 1 and c-kit 2) derived from sequences found in the promoter of the c-kit proto-oncogene.
摘要
荧光共振能量转移分析已被用于研究两种源自 c-kit 原癌基因启动子序列的 DNA G-四链体（c-kit 1 和 c-kit 2）的折叠构象和不同的动力学稳定性。
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