Shenandoah University School of Pharmacy, Winchester, VA 22601, USA.
Obes Surg. 2010 Dec;20(12):1654-9. doi: 10.1007/s11695-009-0050-1. Epub 2010 Jan 27.
The purpose of this study was to describe vitamin and nutrient supplement practices and assess medication dosage formulations utilized in patients hospitalized with a history of bariatric surgery. Retrospective pilot study was conducted from January 1, 2006 through December 31, 2007 in patients with a past history of bariatric surgery. Demographic data, vitamin and nutrient supplements, and medication dosage formulations were evaluated upon admission. This was compared to published guidelines. Compliance with the following supplementation was categorized: daily multivitamin, calcium, iron, vitamin B-12, and folic acid. The frequency of non-immediate-release and enteric-coated medication dosage forms was also examined. Discrepancies were identified as lack of one of the supplements or if an inappropriate dosage formulation was ordered. Of 133 admissions, 117 (88%) had a history of a malabsorptive procedure and at least one discrepancy was found. Only 33.3% of admissions were ordered a multivitamin, 5.1% were ordered supplemental vitamin B-12, and 7.7% received a calcium supplement. Additional folic acid was ordered in 11.1% and iron ordered in 12.0%. Inappropriate medication formulations were ordered in 61.5% of patients; 34.7% included non-immediate-release formulations, 25.0% enteric-coated formulations, and 40.3% both non-immediate-release and enteric-coated. Upon discharge from the institution, 50% had inappropriate formulations continued. Patients with a history of bariatric surgery may not have their vitamin and nutrient needs met upon hospitalization. Prior bariatric surgery is not consistently taken into consideration when ordering medications. Healthcare providers need to be cognizant of vitamin regimens to recommend as well as medication dosage formulations to avoid.
本研究旨在描述接受过减重手术的住院患者的维生素和营养补充剂的使用情况，并评估其用药剂量剂型。本回顾性试点研究于 2006 年 1 月 1 日至 2007 年 12 月 31 日期间在有减重手术史的患者中进行。入院时评估患者的人口统计学数据、维生素和营养补充剂以及用药剂量剂型，并与公布的指南进行比较。根据以下补充剂的使用情况对患者进行分类：每日多种维生素、钙、铁、维生素 B-12 和叶酸。还检查了非即刻释放和肠溶药物剂型的频率。如果发现缺少一种补充剂或开了不合适的剂量剂型，则认为存在差异。在 133 例入院患者中，有 117 例（88%）有过吸收不良手术史，发现至少有 1 种差异。只有 33.3%的入院患者被开具了多种维生素，5.1%的患者被开具了维生素 B-12 补充剂，7.7%的患者接受了钙补充剂。11.1%的患者额外开具了叶酸补充剂，12.0%的患者开具了铁补充剂。61.5%的患者开具了不合适的药物剂型，其中 34.7%为非即刻释放剂型，25.0%为肠溶剂型，40.3%为非即刻释放和肠溶剂型两者均有。出院时，50%的患者仍在继续使用不合适的剂型。接受过减重手术的患者在住院期间可能无法满足其维生素和营养需求。在开具药物时，并未始终考虑到减重手术的病史。医护人员需要了解推荐的维生素方案和避免的药物剂量剂型。
