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腹腔镜右半结肠癌根治术后快速康复的优势。

Advantages of fast-track recovery after laparoscopic right hemicolectomy for colon cancer.

机构信息

Division of Colorectal Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 66905, USA.

出版信息

Surg Endosc. 2010 Aug;24(8):1911-6. doi: 10.1007/s00464-009-0871-y. Epub 2010 Jan 28.

Abstract

BACKGROUND

Fast-track (FT) recovery protocols have demonstrated advantages over historical recovery routines after open colectomy; however, their impact in recovery after laparoscopic colectomy is not clearly defined. This study was designed to determine whether patients who recover on FT protocol after laparoscopic colectomy have a shorter length of stay (LOS) and fewer complications compared with patients who recover on standard (non-FT) protocol.

METHODS

A cohort of consecutive patients with colon cancer who underwent completed laparoscopic-assisted right hemicolectomy from 2005-2007 was identified. Univariate and multivariate logistic analyses were performed to identify risk factors for increased LOS and postoperative complications with recovery protocol as the primary predictor.

RESULTS

A total of 197 patients were included: 115 (58%) patients recovered on a non-FT protocol, and 82 (42%) patients on FT protocol. Univariate analysis showed no differences with respect to age, gender, body mass index, or American Society of Anesthesiologists (ASA) class between groups. The median (interquartile range) LOS was 4 (range, 3-6) days and 3 (range, 3-4) days for the non-FT and FT recovery patients, respectively (p < 0.001). On multivariate analysis, independent risk factors for increased LOS were complications (p < 0.001) and non-FT recovery (p = 0.007). Non-FT recovery also was associated with increased complications (56 vs. 29%, p = 0.0002); this remained significant on multivariate analysis (p < 0.001). Readmissions were similar (p = 1.0) between recovery groups. No mortalities were observed at 30 days.

CONCLUSIONS

Fast-track recovery is independently associated with a shorter LOS and decreased morbidity after laparoscopic right hemicolectomy.

摘要

背景

快速康复(FT)方案在开腹结肠切除术后的恢复中显示出优于传统方案的优势,但在腹腔镜结肠切除术后的恢复效果尚不清楚。本研究旨在确定接受腹腔镜辅助右半结肠切除术的患者在 FT 方案下恢复是否比标准(非 FT)方案下恢复的患者住院时间(LOS)更短,并发症更少。

方法

确定了 2005 年至 2007 年间连续接受腹腔镜辅助右半结肠切除术的结肠癌患者队列。采用单变量和多变量逻辑分析,以确定 LOS 和术后并发症的危险因素,恢复方案为主要预测因素。

结果

共纳入 197 例患者:115 例(58%)患者采用非 FT 方案恢复,82 例(42%)患者采用 FT 方案恢复。单变量分析显示,两组患者在年龄、性别、体重指数或美国麻醉医师协会(ASA)分级方面无差异。非 FT 恢复组和 FT 恢复组的 LOS 中位数(四分位距)分别为 4(3-6)天和 3(3-4)天(p<0.001)。多变量分析显示,LOS 增加的独立危险因素是并发症(p<0.001)和非 FT 恢复(p=0.007)。非 FT 恢复也与并发症增加相关(56%比 29%,p=0.0002);多变量分析仍有统计学意义(p<0.001)。两组患者的再入院率相似(p=1.0)。30 天内无死亡病例。

结论

FT 恢复与腹腔镜右半结肠切除术后 LOS 更短、发病率降低独立相关。

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