Joint Department of Biomedical Engineering, University of North Carolina Chapel Hill and North Carolina State University, Raleigh, NC, USA.
Biotechnol J. 2010 Feb;5(2):192-200. doi: 10.1002/biot.200900250.
In this study, nanoporous gold supercapacitors were produced by electrochemical dealloying of gold-silver alloy. Scanning electron microscopy and energy dispersive X-ray spectroscopy confirmed completion of the dealloying process and generation of a porous gold material with approximately 10 nm diameter pores. Cyclic voltammetry and chronoamperometry of the nanoporous gold electrodes indicated that these materials exhibited supercapacitor behavior. The storage capacity of the electrodes measured by chronoamperometry was approximately 3 mC at 200 mV. Electrochemical storage and voltage-controlled delivery of two model pharmacologic agents, benzylammonium and salicylic acid, was demonstrated. These results suggest that capacitance-based storage and delivery of pharmacologic agents may serve as an alternative to conventional drug delivery methods.
在这项研究中，通过电化学脱合金的方法制备了纳米多孔金超级电容器。扫描电子显微镜和能量色散 X 射线能谱证实了脱合金过程的完成，并生成了一种具有约 10nm 直径孔的多孔金材料。纳米多孔金电极的循环伏安法和计时电流法表明，这些材料表现出超级电容器的行为。通过计时电流法测量的电极存储容量约为 200mV 时的 3mC。证明了两种模型药物（苄基铵和水杨酸）的电化学储存和电压控制释放。这些结果表明，基于电容的药物储存和释放可以作为传统药物输送方法的替代方法。
