Şeker Erkin, Shih Wei-Chuan, Stine Keith J
Department of Electrical and Computer Engineering, Multifunctional Nanoporous Metals Group, University of California, Davis, USA.
Nanobiophotonics Laboratory, and Nanosystem Manufacturing Center, University of Houston, USA.
MRS Bull. 2018 Jan;43(1):49-56. doi: 10.1557/mrs.2017.298. Epub 2018 Jan 10.
Nanoporous metals obtained by dealloying have attracted significant attention for their unusual catalytic properties, and as model materials for fundamental studies of structure-property relationships in a variety of research areas. There has been a recent surge in the use of these metals for biomedical and bioanalytical applications, where many exciting opportunities exist. The goal of this article is to provide a review of recent progress in using nanoporous metals for biological applications, including as biosensors for detecting biomarkers of disease and multifunctional neural interfaces for monitoring and modulating the activity of neural tissue. The article emphasizes the unique properties of nanoporous gold and concludes by discussing its utility in addressing important challenges in biomedical devices.
通过脱合金化获得的纳米多孔金属因其独特的催化性能以及作为各种研究领域中结构-性能关系基础研究的模型材料而备受关注。近年来，这些金属在生物医学和生物分析应用中的使用激增，其中存在许多令人兴奋的机会。本文的目的是综述纳米多孔金属在生物应用方面的最新进展，包括用作检测疾病生物标志物的生物传感器以及用于监测和调节神经组织活动的多功能神经接口。本文强调了纳米多孔金的独特性能，并通过讨论其在应对生物医学设备中的重要挑战方面的效用得出结论。
