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多发性硬化早期的眼部问题。

Ocular problems in early stages of multiple sclerosis.

作者信息

Roodhooft J M

机构信息

National Multiple Sclerosis Centre, v.z.w., Steenokkerzeel, Belgium.

出版信息

Bull Soc Belge Ophtalmol. 2009(313):65-8.

PMID:20108574
Abstract

PURPOSE

In its early course, multiple sclerosis (MS) manifests in a variety of symptoms so that ophthalmologists should know that the ocular problems are often the first sign of the disease and may predict additional demyelinating events.

METHOD

The author have reviewed the data in the recent literature about the ocular problems in the early stages of MS.

RESULTS

The initial signs of MS are: optic neuritis (acute, unilateral), blurred vision, diplopia or oscillopsia (illusory visual motion) due to oculomotor disorder, chronic bilateral uveitis, facial palsy (similar to an idiopathic Bell's palsy), paresthesias, numbness or/and pain in one or more areas innervated by the ramifications of the trigeminal nerve.

CONCLUSION

Ophthalmologists should be aware that these symptoms are suggestive of a demyelinating disease of the central nervous system.

摘要

目的

在早期阶段,多发性硬化症(MS)会表现出多种症状,因此眼科医生应了解眼部问题往往是该疾病的首发症状,并且可能预示着更多的脱髓鞘事件。

方法

作者回顾了近期文献中有关MS早期眼部问题的数据。

结果

MS的初始症状包括:视神经炎(急性、单侧)、视力模糊、由于动眼神经障碍导致的复视或视振荡(虚幻的视觉运动)、慢性双侧葡萄膜炎、面瘫(类似于特发性贝尔面瘫)、感觉异常、三叉神经分支所支配的一个或多个区域的麻木或/和疼痛。

结论

眼科医生应意识到这些症状提示中枢神经系统脱髓鞘疾病。

相似文献

1
Ocular problems in early stages of multiple sclerosis.多发性硬化早期的眼部问题。
Bull Soc Belge Ophtalmol. 2009(313):65-8.
2
The ocular manifestations of multiple sclerosis.多发性硬化的眼部表现。
J Am Optom Assoc. 1977 Dec;48(12):1511-5.
3
Multiple sclerosis and neuro-ophthalmologic manifestations.多发性硬化症与神经眼科表现。
Coll Antropol. 2005;29 Suppl 1:153-8.
4
[Involvement of the visual system in multiple sclerosis].[视觉系统在多发性硬化症中的作用]
Tidsskr Nor Laegeforen. 1993 May 20;113(13):1574-6.
5
Acute inflammatory demyelinating optic neuritis: evidence-based visual and neurological considerations.急性炎症性脱髓鞘性视神经炎:基于证据的视觉和神经学考量
Neurologist. 2008 Jul;14(4):207-23. doi: 10.1097/NRL.0b013e31816f27fe.
6
[Early diagnosis of optic nerve neuropathy in multiple sclerosis].[多发性硬化症中视神经病变的早期诊断]
Klin Oczna. 1996 Jan;98(1):21-5.
7
Multiple sclerosis and vision.多发性硬化与视力。
J Am Optom Assoc. 1986 Dec;57(12):904-8.
8
Ocular manifestations in demyelinating diseases.
Adv Ophthalmol. 1979;39:1-36.
9
Possible association of herpes simplex virus infection with demyelinating disease.单纯疱疹病毒感染与脱髓鞘疾病之间可能存在的关联。
Scand J Infect Dis Suppl. 1985;47:16-21.
10
Early identification of multiple sclerosis through ocularly manifested symptoms.
J Am Optom Assoc. 1979 Feb;50(2):191-2.

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Herpes Simplex Virus 1 Induces Brain Inflammation and Multifocal Demyelination in the Cotton Rat Sigmodon hispidus.单纯疱疹病毒 1 诱导棉鼠 Sigmodon hispidus 脑炎症和多灶性脱髓鞘。
J Virol. 2019 Dec 12;94(1). doi: 10.1128/JVI.01161-19.
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Retinal nerve fiber layer and ganglion cell layer changes on optical coherence tomography in early multiple sclerosis and optic neuritis cases.早期多发性硬化症和视神经炎病例中光学相干断层扫描显示的视网膜神经纤维层和神经节细胞层变化
Indian J Ophthalmol. 2018 Jan;66(1):114-119. doi: 10.4103/ijo.IJO_539_17.
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Uveitis associated with multiple sclerosis: complications and visual prognosis.与多发性硬化相关的葡萄膜炎:并发症及视觉预后
Int J Ophthalmol. 2014 Dec 18;7(6):1010-3. doi: 10.3980/j.issn.2222-3959.2014.06.18. eCollection 2014.
8
Optic neuritis as first clinical manifestations the multiple sclerosis.视神经炎作为多发性硬化症的首发临床表现。
Mater Sociomed. 2014 Aug;26(4):246-8. doi: 10.5455/msm.2014.246-2481. Epub 2014 Aug 26.
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Summary of eye examinations of 284 patients with multiple sclerosis.284例多发性硬化症患者的眼部检查总结
Int J MS Care. 2012 Spring;14(1):31-8. doi: 10.7224/1537-2073-14.1.31.