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[超声检查在透析患者关节淀粉样变诊断中的应用]

[Use of echography for the diagnosis of joint amyloidosis in dialyzed patients].

作者信息

Nessi R, Anelli A, Brancaccio D, Raiteri R, Chiara Bossi M, Uslenghi C

机构信息

Servizio di Nefrologia e Dialisi, Università di Milano, Italia.

出版信息

J Radiol. 1991 Jan;72(1):17-22.

PMID:2010883
Abstract

Amyloid arthropathy is an important complication of long-term hemodialysis. This condition may lead to destructive bone lesions and to severe functional impairment. We studied with sonography of both knees 32 long-term dialysis patients (mean dialytic age: 69.7 months), whose 7 were carrying palpable joint swellings. In 29/32 patients, ultrasound scans were associated with knee X-rays films, patellar views included. In one case, opaque arthrography was performed too. Sonography demonstrated the presence of fluid collections within the articular space and the synovial cavities in 19/32 patients (59%). Their content was transonic or mildly hypoechoic. X-ray films were positive for amyloid bone involvement in 19/29 cases (66%), with intra-osseous cysts and cortical erosions. There was a good general agreement between the results obtained with the two techniques: therefore, in some cases only one examination was positive. Sonography is proposed, in association with standard X-ray films, as a simple and reliable method for the diagnosis of articular amyloidosis in dialysis patients and for the follow-up of this disease.

摘要

淀粉样关节病是长期血液透析的一种重要并发症。这种情况可能导致破坏性骨病变和严重的功能障碍。我们对32例长期透析患者(平均透析年龄:69.7个月)的双膝关节进行了超声检查,其中7例可触及关节肿胀。在32例患者中的29例中,超声扫描与膝关节X线片(包括髌骨关节面)相结合。在1例患者中还进行了关节造影。超声检查显示19/32例患者(59%)关节间隙和滑膜腔内有液体积聚。其内容物为透声或轻度低回声。X线片显示19/29例患者(66%)有淀粉样骨受累,表现为骨内囊肿和皮质侵蚀。两种技术的结果总体上有很好的一致性:因此,在某些情况下只有一种检查呈阳性。建议将超声检查与标准X线片相结合,作为诊断透析患者关节淀粉样变性及其疾病随访的一种简单可靠的方法。

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