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[透析所致骨关节淀粉样变。临床及放射学表现]

[Osteo-articular amyloidosis caused by dialysis. Clinical and radiologic aspects].

作者信息

Baldrati L, Brunetti L, Rocchi A, Bonsanto R, Docci D, Turci F

机构信息

Servizio di Nefrologia e Dialisi, U.S.L. n. 39 Ospedale M. Bufalini, Cesena.

出版信息

Minerva Med. 1990 Oct;81(10):679-82.

PMID:2234460
Abstract

Twenty-nine patients who had received chronic hemodialysis for more than 5 years provided the material for the present study. In 12 of them (41%) there were radiological findings of dialysis related amyloidosis, mainly destructive spondyloarthropathy of the cervical spine (n = 11) and geodes of the shoulder (n = 5). When compared with negative patients, these patients were significantly older (p less than 0.001 and had been dialyzed for longer periods of time (p less than 0.01). Moreover, in such patients there was an higher incidence of carpal tunnel syndrome (p less than 0.025) and shoulder pain (p less than 0.001). Our results confirm that osteoarticular amyloidosis is a frequent long-term complication of chronic hemodialysis and underline the correlation between clinical and radiological findings.

摘要

29例接受慢性血液透析5年以上的患者为本研究提供了材料。其中12例(41%)有透析相关性淀粉样变的影像学表现,主要为颈椎破坏性脊椎关节病(n = 11)和肩部骨囊肿(n = 5)。与阴性患者相比,这些患者年龄显著更大(p < 0.001)且透析时间更长(p < 0.01)。此外,此类患者腕管综合征的发生率更高(p < 0.025)且肩部疼痛发生率更高(p < 0.001)。我们的结果证实骨关节淀粉样变是慢性血液透析常见的长期并发症,并强调了临床和影像学表现之间的相关性。

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