Shakibaei Ghazaleh Imani, Samadi Saadi, Ghahremanzadeh Ramin, Bazgir Ayoob
Department of Chemistry, Shahid Beheshti University, G.C., P.O. Box 19396-4716, Tehran, Iran.
J Comb Chem. 2010 Mar 8;12(2):295-7. doi: 10.1021/cc900169p.
An efficient, simple, and catalyst-free synthesis of dialkyl or diaryl 3-(dicyanomethyl)-2-oxoindolin-3-ylphosphonates by the reaction of dialkyl or diaryl phosphites and oxoindolin-3-ylidenemalononitriles under solvent-free conditions is reported. The reaction of imino isatins with dialkyl or diaryl phosphites results in the formation of dialkyl or diaryl 2-oxo-3-(arylamino)indolin-3-ylphosphonates.
报道了在无溶剂条件下，通过亚磷酸二烷基酯或亚磷酸二芳基酯与氧化吲哚-3-基亚甲基丙二腈反应，高效、简单且无催化剂地合成二烷基或二芳基3-(二氰基甲基)-2-氧代吲哚啉-3-基膦酸酯。亚氨基异吲哚酮与亚磷酸二烷基酯或亚磷酸二芳基酯反应生成二烷基或二芳基2-氧代-3-(芳氨基)吲哚啉-3-基膦酸酯。
