College of Life Sciences, Shenzhen University, Shenzhen 518060, China.
Parasitology. 2010 May;137(6):975-83. doi: 10.1017/S0031182009991879. Epub 2010 Jan 29.
This paper assessed the potential of traditional Chinese medicine (TCM) preparations for using as environmentally acceptable and alternative commercial acaricides.
22 kinds of TCM, which contained abundant essential oils and showed insecticidal effects, were collected. Samples extracted with petroleum ether, ethyl acetate and methanol were tested against house dust mites Dermatophagoides farinae and their toxicity assessed.
The results showed that 3 TCM of Cinnamonum cassia, Eugenia caryophyllata and Pogostemon cablin have higher activity, and the parallel tests showed that the petroleum ether extract had higher activities (0.0046 mg/cm2, 0.005 mg/cm2 and 0.006 mg/cm2 respectively, 24 h, LD50) than the extracts of ethyl acetate and methanol. The acaricidal activity of the ethyl acetate extracts from C. cassia, P. cablin and Asarum sieboldii (0.00144 mg/cm2, 0.00347 mg/cm2 and 0.05521 mg/cm2 respectively, 24 h, LD50) were almost comparable to that of benzyl benzoate and dibutyl phthalate. However, the methanolic extracts of were less effective. CONCLUSIONS. This study shows the use of extracts with petroleum ether of C. cassia, P. cablin and E. caryophyllata as eco-friendly biodegradable agents for the control of the house dust mite.
本文评估了中药（TCM）制剂作为环保且可替代商业杀螨剂的潜力。
收集了 22 种含有丰富精油且具有杀虫效果的中药。用石油醚、乙酸乙酯和甲醇提取样品，测试其对粉尘螨（Dermatophagoides farinae）的毒性。
结果表明，肉桂、丁香和藿香 3 种中药活性较高，平行试验表明，石油醚提取物活性更高（24 hLD50 分别为 0.0046mg/cm2、0.005mg/cm2 和 0.006mg/cm2），高于乙酸乙酯和甲醇提取物。肉桂、藿香和细辛的乙酸乙酯提取物（24 hLD50 分别为 0.00144mg/cm2、0.00347mg/cm2 和 0.05521mg/cm2）的杀螨活性几乎与苯甲酸苄酯和邻苯二甲酸二丁酯相当，但甲醇提取物的效果较差。
本研究表明，使用肉桂、藿香和丁香的石油醚提取物作为环保、可生物降解的杀螨剂控制尘螨具有一定的应用潜力。
