Department of Otolaryngology, P.O. Box 9200, West Virginia University, Morgantown WV 26506-9200, USA.
Am J Rhinol Allergy. 2010 Jan-Feb;24(1):e54-6. doi: 10.2500/ajra.2010.24.3431.
Balloon catheter sinuplasty (BCS) for chronic rhinosinusitis (CRS) was found to be successful in adults. The safety and feasibility of BCS in children has been recently established. The purpose of this study was to study the outcome of this technology in CRS in children.
A prospective, multicenter, nonrandomized evaluation was performed on patients with CRS. Thirty-two children between the ages of 2 and 11 years were enrolled. Safety was assessed by rate of adverse events. Effectiveness was assessed using the Sino-Nasal (SN)-5 quality-of-life questionnaire for children with CRS at 52 weeks follow-up.
Thirty-two children were enrolled of which 24 completed their 52 weeks follow-up. No adverse events were reported because of the procedure. SN-5 score improved from a mean of 4.9 at baseline to a mean of 2.95 at 52 weeks (p < 0.0001). Twelve (50%) children had a significant improvement of their SN-5 (>-1.5), 7 (29%) had moderate improvement (>-1.0 and <-1.5), 2 (8%) had mild improvement (>-0.5 and <-1.0), 1 (4%) remained the same, and 2 (8%) had worsening scores.
Balloon catheter dilation of the sinus ostia in children was safe and a significant number showed improvement of their SN-5 at 1 year follow-up. Additional studies comparing balloon sinuplasty to other modalities of treatment in children are needed to determine its efficacy in the treatment of CRS in children.
球囊导管鼻内鼻窦切开术（BCS）治疗慢性鼻-鼻窦炎（CRS）在成人中已被证实是成功的。BCS 在儿童中的安全性和可行性最近已经得到证实。本研究的目的是研究该技术在儿童 CRS 中的疗效。
对患有 CRS 的患者进行了前瞻性、多中心、非随机评估。共纳入 32 名年龄在 2 至 11 岁之间的儿童。通过不良事件发生率评估安全性。通过 Sino-Nasal (SN)-5 儿童 CRS 生活质量问卷在 52 周随访时评估有效性。
共纳入 32 名儿童，其中 24 名完成了 52 周随访。由于该程序，没有报告不良事件。SN-5 评分从基线时的平均 4.9 分改善至 52 周时的平均 2.95 分（p<0.0001）。12 名（50%）儿童的 SN-5 显著改善（>-1.5），7 名（29%）有中度改善（>-1.0 和 <-1.5），2 名（8%）有轻度改善（>-0.5 和 <-1.0），1 名（4%）保持不变，2 名（8%）评分恶化。
儿童鼻窦口球囊扩张术是安全的，大量患儿在 1 年随访时 SN-5 评分得到改善。需要进一步的研究比较球囊鼻窦切开术与儿童其他治疗方式的疗效，以确定其在儿童 CRS 治疗中的效果。
