Department of International Health, Georgetown University, Washington, DC 20007, USA.
Lancet. 2010 Jan 2;375(9708):67-76. doi: 10.1016/S0140-6736(09)61749-9.
Neglected tropical diseases represent one of the most serious burdens to public health. Many can be treated cost-effectively, yet they have been largely ignored on the global health policy agenda until recently. In this first paper in the Series we review the fragmented structure of elimination and control programmes for these diseases, starting with the ambiguous definition of a neglected tropical disease. We describe selected international control initiatives and present their effect, governance arrangements, and financing mechanisms, including substantial drug-donation programmes. We also discuss efforts to exploit shared features of these diseases by integration of selected control activities within countries, thus creating economies of scope. Finally we address the challenges, resulting from the diversity of disease control approaches and governance structures-both nationally and internationally-and provide some suggestions for the way forward.
被忽视的热带病是对公共卫生的最大威胁之一。许多疾病的治疗成本效益很高，但直到最近，它们在全球卫生政策议程中才被广泛忽视。在本系列的第一篇论文中，我们从被忽视的热带病的模糊定义开始，回顾了这些疾病的消除和控制规划的分散结构。我们描述了一些国际控制倡议，并介绍了它们的效果、治理安排和融资机制，包括大量的药物捐赠计划。我们还讨论了通过在国家内部整合选定的控制活动来利用这些疾病的共同特征的努力，从而创造范围经济。最后，我们讨论了由于国家和国际上的疾病控制方法和治理结构的多样性所带来的挑战，并为未来的发展提供了一些建议。
