Chao T C, Greager J A
Department of Surgery, University of Illinois College of Medicine, Chicago 60612.
J Surg Oncol. 1991 Mar;46(3):145-50. doi: 10.1002/jso.2930460303.
Thirty-seven patients with carcinoma of the extrahepatic bile ducts (EHBD), diagnosed over 14 years from 1974 to 1987, were studied retrospectively. The most common presenting complaint was jaundice, followed by abdominal pain, nausea and vomiting, and weight loss. The majority of EHBD carcinomas were located at the middle third of the bile duct (43.2%), followed by upper third bile duct (37.8%), and lower third bile duct (18.9%). The resectability of the surgically managed group was 44.4%. The most common histologic type was adenocarcinoma. The 30-day postoperative mortality was 30.6%. The mean overall survival of the patients with EHBD carcinoma was 11.2 months. Patients with distal third tumors had the best prognosis with a mean overall survival of 16.0 months. The mean overall survival of patients with upper-third and middle-third tumors were 10.9 months and 9.4 months. A high index of suspicion of the disease as well as earlier, aggressive surgery may improve patient survival.
对1974年至1987年14年间确诊的37例肝外胆管癌（EHBD）患者进行了回顾性研究。最常见的主诉是黄疸，其次是腹痛、恶心呕吐和体重减轻。大多数EHBD癌位于胆管的中三分之一处（43.2%），其次是上三分之一胆管（37.8%）和下三分之一胆管（18.9%）。手术治疗组的可切除率为44.4%。最常见的组织学类型是腺癌。术后30天死亡率为30.6%。EHBD癌患者的平均总生存期为11.2个月。远端三分之一肿瘤患者的预后最佳，平均总生存期为16.0个月。上三分之一和中三分之一肿瘤患者的平均总生存期分别为10.9个月和9.4个月。对该病高度怀疑以及早期积极手术可能会提高患者生存率。
